Grundinformationen
- CAS
134-09-8- Standard-SMILES
CC1CCC(C(C)C)C(OC(=O)c2ccccc2N)C1- InChIKey
SOXAGEOHPCXXIO-UHFFFAOYSA-N- Summenformel
- C17H25NO2
- Durchschnittliche Molmasse
- 275,4 g/mol
- Monoisotopische Masse
- 275,18852904
Überblick
Meradimate is a monoterpenoid.
Namen und Bezeichner
- Bevorzugter Name
- Menthyl Anthranilate
- IUPAC
- (5-methyl-2-propan-2-ylcyclohexyl) 2-aminobenzoate
- Lokaler Name
- Menthylanthranilat
- Englischer Name
- Menthyl anthranilate
- Summenformel
- C17H25NO2
- Molmasse
- 275.39
Namen und Synonyme
MENTHYL ANTHRANILATE134-09-8MeradimateAnthranilic acid, p-menth-3-yl esterMeradimatoDTXSID3047895Cyclohexanol, 5-methyl-2-(1-methylethyl)-, 2-aminobenzoateJ9QGD60OUZDTXCID3027871meradimatumRefChem:925487205-129-8
Weitere Namen anzeigen
MERADIMATE,USPMenthyl o-aminobenzoateMENTHYL ANTHRANILATE, USP STANDARDMenthyl Anthranilate (500 mg/ampule) (Meradimate)Meradimate (500 mg/ampule) (Menthyl Anthranilate)5-methyl-2-(1-methylethyl)-cyclohexano2-aminobenzoateHigh purity CAS 134-09-8 Menthyl anthranilate in stock
Meradimate [INN]Menthyl-O-aminobenzoate(5-methyl-2-propan-2-ylcyclohexyl) 2-aminobenzoate5-methyl-2-(propan-2-yl)cyclohexyl 2-aminobenzoate2-isopropyl-5-methylcyclohexyl 2-aminobenzoateNCGC00159361-02Cyclohexanol,5-methyl-2-(1-methylethyl)-, 1-(2-aminobenzoate)CAS-134-09-8
Datenbank-Bezeichner
- CAS
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 5,1
- Polarare Oberfläche (TPSA)
- 52,3 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 3
- Frei drehbare Bindungen
- 4
- Schwere Atome
- 20
- Formalladung
- 0
- Komplexität
- 329
Experimentelle und physikochemische Eigenschaften
CosmeticsUv absorber
SolubilityInsoluble
Boiling Point177-179 ºC
Physikochemische Eigenschaften
- Schmelzpunkt
- 62.5 · 62.5-63.5°
- Siedepunkt
- 177 · 177-179 °C3 mm Hg(lit.)
- Dichte
- 1.04 g/mL · 1.04 g/mL at 25 °C(lit.)
- Brechungsindex
- 20 · n20/D 1.542(lit.)
- Flammpunkt
- 230 °F · >230 °F
- storage temp.
- 2 · 2-8°C
- Aggregatzustand
- liquid
- pka
- 2.17 · 2.17±0.10(Predicted)
- Geruch (Odor)
- 100 % · at 100.00 %. grape menthol
- Geruchsart
- fruity
- Kosmetik-Inhaltsstoffe Funktionen
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 64 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Regulatory Information
Chemical: Cyclohexanol, 5-methyl-2-(1-methylethyl)-, 2-aminobenzoate
Cyclohexanol, 5-methyl-2-(1-methylethyl)-, 2-aminobenzoate: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Sicherheitsdaten
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 2922493800
- risk_code
- 36/37/38
- hazard_code
- Xi
- safety_code
- 26-36
- Speicherklasse
- 10 - Combustible liquids
- Hazard Classifications
- Eye Irrit. 2Skin Irrit. 2STOT SE 3
Chemie und Industrie
Pharmakologische Informationen
Protein BindingAs meradimate is not absorbed, this pharmacokinetic property is not relevant.
PharmacodynamicsMeradimate effect provides a low-level, broad-spectrum protecting coverage effect.
Mechanism of Action
Meradimate acts by absorbing both the UVA and UVB radiation, this provides this ingredient with a broad spectrum and it explains why it is highly used in different products such as lip balms, lipsticks, and moisturizers. Its protective effective action does not cover completely the UVA rays as it only reaches 336 nm. This has been proven even thought meradimate has a theoretical protective coverage range between 200-380 nm. Its function is related to the intrinsic structure of meradimate which is an ortho-disubstituted aminobenzoate. This structure allows easy electron delocalization and shifts in the maximum absorption.
Biological Half-LifeAs meradimate is not absorbed, this pharmacokinetic property is not relevant.
Metabolism/MetabolitesAs meradimate is not absorbed, this pharmacokinetic property is not relevant.
Absorption, Distribution and Excretion
Meradimate is not absorbed through the skin.
As meradimate is not absorbed, this pharmacokinetic property is not relevant.
As meradimate is not absorbed, this pharmacokinetic property is not relevant.
As meradimate is not absorbed, this pharmacokinetic property is not relevant.
Verwendung und Herstellung
Household ProductsInformation on 1 consumer products that contain Menthyl anthranilate in the following categories is provided:
Use ClassificationCosmetics -> Uv absorber
Zugehörige Reaktionen
2
Notizen zur Verbindung
Wird geladen…