Bromcyclopentan
CYCLOPENTYL BROMIDE · Cyclopentane Bromide · Bromocylopentane · bromo-cyclopentan · BROMOCYCLOPENTANE · AKOS BBS-00004279 · 1-Bromocyclopentane · Cyclopentane,bromo-
Identifikatoren & physikalische Daten
| CAS No. | 137-43-9 |
|---|---|
| Summenformel | C5H9Br |
| Durchschnittliche Molmasse | 149,03 g/mol |
| Monoisotopische Masse | 147,98876239 g/mol |
| SMILES | BrC1CCCC1 |
| InChIKey | BRTFVKHPEHKBQF-UHFFFAOYSA-N |
| PubChem CID | 8728 |
| EC No. | 205-294-6 |
| DTXSID | DTXSID9059670 |
| Lokaler Name | Bromcyclopentan |
Chemische & physikalische Eigenschaften
| XLogP | 2,3 |
|---|---|
| Polarare Oberfläche (TPSA) | 0 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 0 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 6 |
| Formalladung | 0 |
| Komplexität | 37,2 |
| SpringerMaterials Properties | Schoenflies notation |
| Siedepunkt | 137-139 °C (lit.) |
| Dichte | 1.39 g/mL at 25 °C (lit.) |
| Brechungsindex | n20/D 1.4881(lit.) |
| Flammpunkt | 95 °F |
| Lagerbedingungen | Store at R.T. |
| Löslichkeit | Chloroform, Ethyl Acetate (Slightly)Immiscible with water. |
| Aggregatzustand | Liquid |
| Wichte | 1.39 |
| Farbe | Clear yellow to light brown |
| BRN | 1209256 |
| Stabilität | Stable. Flammable. Incompatible with strong oxidizing agents, strong bases. |
| InChI | 1S/C5H9Br/c6-5-3-1-2-4-5/h5H,1-4H2 |
| InChIKey | BRTFVKHPEHKBQF-UHFFFAOYSA-N |
| SMILES | BrC1CCCC1 |
| LogP (Verteilungskoeffizient) | 2.745 (est) |
| CAS Datenbank | 137-43-9(CAS DataBase Reference) |
| NIST chemische Informationen | Cyclopentane, bromo-(137-43-9) |
| EPA chemische Informationen | Cyclopentane, bromo- (137-43-9) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH226 (98.8%): Flammable liquid and vapor [Warning Flammable liquids]P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 82 reports by companies from 5 notifications to the ECHA C&L Inventory. |
|---|---|
| Regulatorische Informationen | Chemical: Cyclopentane, bromo-Status: Active Update: 12-02-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/15852Bromocyclopentane: Does not have an individual approval but may be used under an appropriate group standard |
| Hazard Classes and Categories | Flam. Liq. 3 (98.8%) |
| F | 8 |
| Wassergefährdungsklasse (WGK) | 3 |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | UN 1993 3/PG 3 |
| Zollcode | 29035990 |
| R-Sätze (R) | 10 |
| Sicherheitshinweise (S) | 23-24/25-16 |
| Gefahrenklasse | 3Flam. Liq. 3 |
| Verpackungsgruppe | III |
| Lagerklasse | 3 - Flammable liquids |
Anwendungen & Verwendung
Verwenden
Bromocyclopentane is a precursor used in the preparation of cyclopentene and cyclopentanol. It is a fatty bromide, which is used as a solvent. It is used as an intermediate for the preparation of surfactant and pharmaceuticals and other organic compounds. It is also used in the production of the medicine cyclopentathiazide.
Herstellung & Synthese
synthetische
Bromocyclopentane is synthesized by bromination of cyclopentanol: cyclopentanol is mixed with hydrobromic acid and heated to about 170°C refluxed for 6-8h. Then distilled with water steam, the oil layer is washed with 5% sodium carbonate, then dried, filtered, fractionated and collected 136-139°C fraction is the finished product. Another method is by the reaction of cyclopentanol and phosphorus tribromide: the cyclopentanol is cooled to 0 ℃, add the newly evaporated phosphorus tribromide drop by drop, add it all at 0-5 ℃, stir for 2h, and leave it at room temperature overnight. Add water and stratify, take the oil layer water distillation. Distillate stratification, the oil layer was washed with 10% sodium bicarbonate solution, dried with anhydrous calcium chloride, filtration, filtrate distillation, collect 134-141 ℃ fraction that is bromocyclopentane.