2,6-Difluorbenzamid

2,6-Difluorobenzamide

HCID 87439CAS 18063-03-1
TeilstruktursucheÄhnliche Strukturen suchen

Grundinformationen

Standard-SMILES
NC(=O)c1c(F)cccc1F
InChIKey
AVRQBXVUUXHRMY-UHFFFAOYSA-N
Summenformel
C7H5F2NO
Durchschnittliche Molmasse
157,12 g/mol
Monoisotopische Masse
157,03392022

Überblick

structure given in first source

Namen und Bezeichner

Bevorzugter Name
2,6-Difluorobenzamide
IUPAC
2,6-difluorobenzamide
Lokaler Name
2,6-Difluorbenzamid
Englischer Name
2,6-Difluorobenzamide
Summenformel
C7H5F2NO
Molmasse
157.12

Namen und Synonyme

2,6-Difluorobenzamide18063-03-1Benzamide, 2,6-difluoro-SJ2RN214MKDTXSID4073417RefChem:445557DTXCID6035734241-972-8MFCD000079722,6-difluorobenzoic amideUNII-SJ2RN214MKEC 241-972-8
Weitere Namen anzeigen
2,6-difluorobenzoic acid amideuorobenzamideCompound Fr139742,6-Difluorbenzamid2,6-difluoro-benzamid2，6-difluorobenzaminde2,6-Difluorobenzoamide2,6-Difluorobenzoylamide2,6-Difluorobenzamide97%
CK1202PS-8830SB67309Z1044761382,6-difluoro benzamideEINECS 241-972-8Benzamide, 2,6-difluoro-; 2,6-Difluorobenzamide; Lufenuron Imp. A (EP)2,6 difluorobenzamide

Datenbank-Bezeichner

CAS
18063-03-1
PubChem CID
87439
DTXSID
DTXSID4073417
UNII
SJ2RN214MK
EC Number
241-972-8
Nikkaji
J43.076E

Eigenschaften

Berechnete Struktureigenschaften

XLogP
0,3
Polarare Oberfläche (TPSA)
43,1 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
3
Frei drehbare Bindungen
1
Schwere Atome
11

Experimentelle und physikochemische Eigenschaften

PesticidesEnvironmental transformation -> Pesticide transformation products (metabolite, successor)
LogP0.25

Physikochemische Eigenschaften

Schmelzpunkt
145 · 145-148 °C (lit.)
Siedepunkt
51 · 51-52C/15Tor
Dichte
1 · 1,199g/cm
Brechungsindex
1 · 1,508
storage temp.
Sealed in dry,Room Temperature
Löslichkeit
5 %, · ethanol: soluble5%, clear to turbid, colorless to light yellow

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

This chemical does not meet GHS hazard criteria for 21.5% (56 of 260) of reports.

Warning

H302 (42.7%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 260 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory Information · 4 Einträge

Chemical: Benzamide, 2,6-difluoro-

Commission Regulation No 844/2012

PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Status: Active Update: 13-08-2015 https://echa.europa.eu/registration-dossier/-/registered-dossier/5759

Hazard Classes and CategoriesAcute Tox. 4 (42.7%)

Sicherheitsdaten

wgk
1
tsca
TSCA listed
hs_code
29242990
RTECS-Nr.
CV4355050
risk_code
36/37/38-20
Toxizität
rat,LC50,inhalation,> 2100mg/m3/4H (2100mg/m3),National Technical Information Service. Vol. OTS0543293,

Chemie und Industrie

Verwendung und Herstellung

Use ClassificationEnvironmental transformation -> Pesticide transformation products (metabolite, successor)
General Manufacturing InformationBenzamide, 2,6-difluoro-: ACTIVE
Anwendungen · 3 Einträge

Beschreibung2,6-Difluorobenzamide is a white powdery crystal, insoluble in water. It can be obtained by hydrolysis of 2,6-difluorobenzonitrile. 2,6-Difluorobenzamide is an important intermediate in the synthesis process of benzoylurea insecticides, which is used to synthesize the next intermediate 2,6-difluorobenzoyl isocyanate, and finally obtain flubolurea, pyruron, fluridin, lice mite urea and other pesticide varieties. It can also be directly used to synthesize pyruron and flubolea. 2,6-Difluorobenzamide can inhibit the bacterial cell division protein FtsZ[1].

Beschreibung2,6-Difluorobenzamide is a major metabolite of pesticide diflubenzuron and has been quantitated by HPLC/diode-array method.

Verwenden2,6-Difluorobenzamide (CAS# 18063-03-1) is a useful building block used in the synthesis of (E)-3-methyleneisoindolin-1-ones via oxidative annulation acrylates. It is also used in the synthesis of pesticide intermediates, which can be used to produce various insecticides such as fluazuron, chlorpyrifos, and pyrethroids.

Darstellung

synthetische2,6-Difluorobenzamide is obtained by hydrolysis of 2,6-difluorobenzonitrile.

Vor- und nachgelagerte Produkte

Anbieter50 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海恩氟佳科技有限公司15800445152 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
T&W GROUP021-61551611 13296011611 · [email protected]

Zugehörige Reaktionen

62
Reaktionsaufzeichnung erstellen

Verknüpfte Notizen

Wird geladen…