6-Chloro-2-picoline (HCID 87601)

Namen und Bezeichner

Bevorzugter Name: 6-Chloro-2-picoline
IUPAC: 2-chloro-6-methylpyridine
Lokaler Name: 6-Chlor-2-methylpyridin
Englischer Name: 2-Chloro-6-methylpyridine
Summenformel: C6H6ClN
Molmasse: 127.57

Namen und Synonyme

2-Chloro-6-methylpyridine6-Chloro-2-picoline6-Chloro-2-methylpyridine6-methyl-2-chloropyridineEINECS 242-241-6UNII-39MX1LQ68L39MX1LQ68L2-Cl-6-(CH3)-pyridineDTXSID0022272RefChem:104387DTXCID502272GXZDYRYYNXYPMQ-UHFFFAOYSA-N

Weitere Namen anzeigen

6-CHLORO-ALPHA-PICOLINEC2346-CH6-Chloropicoline2-Chloro-6-Pilcoline6-Chloro-2-picoline,98%

18368-63-3Pyridine, 2-chloro-6-methyl-2-Chloro-6-picoline2-Picoline, 6-chloro-MFCD000062452-chloro-6-methyl-pyridineSCHEMBL73851SCHEMBL111063

Datenbank-Bezeichner

CAS: 18368-63-3
PubChem CID: 87601
DTXSID: DTXSID0022272
UNII: 39MX1LQ68L
EC Number: 242-241-6
Nikkaji: J100.611H

Eigenschaften

Berechnete Struktureigenschaften

XLogP: 2,2
Polarare Oberfläche (TPSA): 12,9 Å²
H-Brücken-Donoren: 0
H-Brücken-Akzeptoren: 1
Frei drehbare Bindungen: 0
Schwere Atome: 8
Formalladung: 0
Komplexität: 74

Physikochemische Eigenschaften

Siedepunkt: 64 · 64-68 °C10 mm Hg(lit.)
Dichte: 1.167 g/mL · 1.167 g/mL at 25 °C(lit.)
Brechungsindex: 20 · n20/D 1.527(lit.)
Flammpunkt: 165 °F · 165 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: 1.1 · 1.10±0.10(Predicted)
Aggregatzustand: Liquid
Farbe: Clear colorless to light yellow
Wichte: 1.167 · 1.167
BRN: 107187 · 107187
InChI: InChI=1S/C6H6ClN/c1-5-3-2-4-6(7)8-5/h2-4H,1H3
InChIKey: GXZDYRYYNXYPMQ-UHFFFAOYSA-N
SMILES: C1(Cl)=NC(C)=CC=C1
CAS Datenbank: 18368 · 18368-63-3(CAS DataBase Reference)
NIST chemische Informationen: 2 · 2-Cl-6-(CH3)-pyridine(18368-63-3)
EPA chemische Informationen: 2 · Pyridine, 2-chloro-6-methyl- (18368-63-3)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

Warning

H302 (14.9%): Harmful if swallowed [Warning Acute toxicity, oral]；H312 (14.9%): Harmful in contact with skin [Warning Acute toxicity, dermal]；H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H332 (14.9%): Harmful if inhaled [Warning Acute toxicity, inhalation]；H335 (97.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 47 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Hazard Classes and CategoriesAcute Tox. 4 (14.9%)；Acute Tox. 4 (14.9%)；Skin Irrit. 2 (100%)；Eye Irrit. 2 (100%)；Acute Tox. 4 (14.9%)；STOT SE 3 (97.9%)

Sicherheitsdaten

wgk: 3
ridadr: UN2810
hs_code: 29333990
risk_code: 36/37/38-20/21/22
hazard_code: Xi,Xn
hazard_note: Irritant
safety_code: 26-36-36/37/39
hazard_class: 6.1
packing_group: III
Speicherklasse: 10 - Combustible liquids
Hazard Classifications: Eye Irrit. 2Skin Irrit. 2STOT SE 3

Chemie und Industrie

Anwendungen · 2 Einträge

Beschreibung2-Chloro-6-methylpyridine (2C6MP) is a strong inhibitor of methane monooxygenase, a key enzyme in the aerobic oxidation of methane (CH4). It belongs to the pesticide nitropyridine group of compounds. Studies have shown that 2C6MP has the least effect on CH4 oxidation at concentrations of 0.1 mM and 1 mM, but at a concentration of 10 mM, 2C6MP inhibits CH4 oxidation for >20 months. Low concentrations of 2C6MP did not inhibit Methylophilaceae, while high concentrations of 2C6MP inhibited Methylophilaceae by only 7.8 ± 1.1%[1].

Verwenden2-Chloro-6-methylpyridine has been used for experimental FTIR and FT-Raman spectroscopic analyses, as well as for conformational studies.