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HCID 87809Erstellt: 4. November 2026

Manganese sulfide (MNS)

https://huagongshe.com/de/chemical/87809

Molekülstruktur von Manganese sulfide (MNS)

Identifikatoren & physikalische Daten

CAS No.18820-29-6
SummenformelMnS
Durchschnittliche Molmasse87,01 g/mol
Monoisotopische Masse86,910114 g/mol
SMILES[S]=[Mn]
InChIKeyCADICXFYUNYKGD-UHFFFAOYSA-N
PubChem CID87809
EC No.242-599-3
DTXSIDDTXSID00893974

Chemische & physikalische Eigenschaften

Polarare Oberfläche (TPSA)32,1
H-Brücken-Donoren0
H-Brücken-Akzeptoren1
Frei drehbare Bindungen0
Schwere Atome2
Formalladung0
Komplexität2
StoffklassenMetals -> Manganese Compounds, Inorganic
Dichte4 @25 °C
Schmelzpunkt1610 °C
Physical DescriptionPink, green, or brown-green solid[Merck Index]

Sicherheit & Vorschriften

GHS-EinstufungThis chemical does not meet GHS hazard criteria for 7.5% (25 of 333) of reports.DangerH315 (91%): Causes skin irritation [Warning Skin corrosion/irritation]P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 333 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Regulatorische InformationenManganese sulfide (MnS) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Manganese sulfide (MnS) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)REACH registered substance: Manganese sulphide (EC: 242-599-3)Manganese sulfide (MnS): Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
GefahrenübersichtToxic by ingestion[MSDSonline] See Manganese and linked occupational diseases.
Hazard Classes and CategoriesSkin Irrit. 2 (91%)
Expositionsschutz und Persönliche Schutzausrüstung0.2 [mg/m3], as Mn (inhalable fraction), 0.02 mg/m3, as Mn (respirable fraction)[German Research Foundation (DFG)]
Minimum Risk LevelChronic Inhalation: 0.0003 mg/m3 (L134)
Threshold Limit Values (TLV)0.02 [mg/m3], as Mn (respirable fraction), 0.1 mg/m3, as Mn (inhalable fraction)
Protective Action Criteria (PAC)4.8 [mg/m3]7.9 [mg/m3]790 [mg/m3]
TreatmentEYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration.
Gesundheitliche AuswirkungenManganese mainly affects the nervous system and may cause behavioral changes and other nervous system effects, which include movements that may become slow and clumsy. This combination of symptoms when sufficiently severe is referred to as “manganism”. (L228)
Unerwünschte WirkungenNeurotoxin - Parkinsonism
ExpositionspfadeOral (L228)inhalation (L228)
ToxizitätsübersichtManganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particularily the globus pallidus of the basal ganglia. It is believed that the manganese ion, Mn(II), enhances the autoxidation or turnover of various intracellular catecholamines, leading to increased production of free radicals, reactive oxygen species, and other cytotoxic metabolites, along with a depletion of cellular antioxidant defense mechanisms, leading to oxidative damage and selective destruction of dopaminergic neurons. In addition to dopamine, manganese is thought to perturbations other neurotransmitters, such as GABA and glutamate. In order to produce oxidative damage, manganese must first overwhelm the antioxidant enzyme manganese superoxide dismutase. The neurotoxicity of Mn(II) has also been linked to its ability to substitute for Ca(II) under physiological conditions. It can enter mitochondria via the calcium uniporter and inhibit mitochondrial oxidative phosphorylation. It may also inhibit the efflux of Ca(II), which can result in a loss of mitochondrial membrane integrity. Mn(II) has been shown to inhibit mitochondrial aconitase activity to a significant level, altering amino acid metabolism and cellular iron homeostasis. (L228)
Signs and SymptomsManganese mainly affects the nervous system and may cause behavioral changes and other nervous system effects, which include movements that may become slow and clumsy. This combination of symptoms when sufficiently severe is referred to as “manganism”. (L228)
Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).