HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
6-Phenyl-2-pyridon
Phenylpyridone · Einecs 242-740-9 · 6-PHENYL-2-PYRIDONE · 6-phenylpyridin-2-ol · 6-Phenylpyridin-2(1H) · 6-Phenylpyridine-2-ol · 6-Phenyl-2-pyridone>6-phenyl-2-pyridone95+% · 6-Phenyl-2(1H)-pyridone
Identifikatoren & physikalische Daten
| CAS No. | 19006-82-7 |
|---|---|
| Summenformel | C11H9NO |
| Durchschnittliche Molmasse | 171,199 g/mol |
| Monoisotopische Masse | 171,06841391 g/mol |
| SMILES | O=c1cccc(-c2ccccc2)[nH]1 |
| InChIKey | ZLUIDXRFWSPPCC-UHFFFAOYSA-N |
| PubChem CID | 87889 |
| ChEMBL | CHEMBL1730128 |
| EC No. | 242-740-9 |
| DTXSID | DTXSID40172472 |
| Lokaler Name | 6-Phenyl-2-pyridon |
Chemische & physikalische Eigenschaften
| XLogP | 1,8 |
|---|---|
| Polarare Oberfläche (TPSA) | 29,1 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 13 |
| Formalladung | 0 |
| Komplexität | 259 |
| Schmelzpunkt | 197 °C |
| Siedepunkt | 417.1±38.0 °C(Predicted) |
| Dichte | 1.158±0.06 g/cm3(Predicted) |
| Lagerbedingungen | Sealed in dry,2-8°C |
| pKa (Säurekonstante) | 10.82±0.10(Predicted) |
| Aggregatzustand | powder to crystal |
| Farbe | White to Orange to Green |
| InChI | 1S/C11H9NO/c13-11-8-4-7-10(12-11)9-5-2-1-3-6-9/h1-8H,(H,12,13) |
| InChIKey | ZLUIDXRFWSPPCC-UHFFFAOYSA-N |
| SMILES | O=C1NC(=CC=C1)c2ccccc2 |
| CAS Datenbank | 19006-82-7 |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH302 (97.5%): Harmful if swallowed [Warning Acute toxicity, oral]H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P330, P337+P317, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 40 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Hazard Classes and Categories | Acute Tox. 4 (97.5%)Eye Irrit. 2 (100%) |
| Wassergefährdungsklasse (WGK) | 3 |
| Zollcode | 2933399990 |
| R-Sätze (R) | 22-36 |
| Gefahrensymbole | Xn |
| Sicherheitshinweise (S) | 26 |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrenklasse | Acute Tox. 4 OralEye Irrit. 2 |
Anwendungen & Verwendung
Verwenden
6-Phenylpyridin-2(1H)-one is used as a reactant in the preparation of phenylaminopyrimidinones and its derivatives as orally active nonpeptidic inhibitors of human neutrophil elastase.