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2,2'-Dithiodibenzoylchlorid
Einecs 243-180-8 · 2,2'-dithiodibenzoyl chloride · 2,2'-Dithiodibenzoyl dichloride · Benzoyl chloride, 2,2'-dithiobis- · 2,2'-dithiodibenzoic acid dichloride · 2,2'-disulfanediyldibenzoyl chloride · 2-[(2-carbonochloridoylphenyl)disulfanyl]benzoylchloride
Identifikatoren & physikalische Daten
| CAS No. | 19602-82-5 |
|---|---|
| Summenformel | C14H8Cl2O2S2 |
| Durchschnittliche Molmasse | 343,2 g/mol |
| Monoisotopische Masse | 341,93427686 g/mol |
| SMILES | O=C(Cl)c1ccccc1SSc1ccccc1C(=O)Cl |
| InChIKey | DSFZYLCRXIWFFW-UHFFFAOYSA-N |
| PubChem CID | 88164 |
| EC No. | 243-180-8 |
| DTXSID | DTXSID70173270 |
| Lokaler Name | 2,2'-Dithiodibenzoylchlorid |
Chemische & physikalische Eigenschaften
| XLogP | 5 |
|---|---|
| Polarare Oberfläche (TPSA) | 84,7 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 4 |
| Frei drehbare Bindungen | 5 |
| Schwere Atome | 20 |
| Formalladung | 0 |
| Komplexität | 331 |
| Schmelzpunkt | 153 °C |
| Siedepunkt | 443.7±30.0 °C(Predicted) |
| Dichte | 1.51±0.1 g/cm3(Predicted) |
| LogP (Verteilungskoeffizient) | 4.790 (est) |
Anwendungen & Verwendung
Verwenden
2,2''-Disulfanediyldibenzoyl Chloride is an intermediate used in the synthesis of N,N’-Bis(2-mercaptobenzoyl)hydrazide (B481825), which is a selective inhibitor of HIV-1 integrase. Has no other effect on other retroviral targets, including reverse transcriptase, protease, and virus attachement, and exhibits no detectable activity against human topoisomerases I and II at concentrations that effectively inhibit integrase.