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Aniliniumchlorid
ANILINE HCL · ANILINIUM CHLORIDE · Anilinhydrochlorid · C.I. 76001 · usafek-442 · Aniline salt · sulanilinova · chloridanilinu
Identifikatoren & physikalische Daten
| CAS No. | 142-04-1 |
|---|---|
| Summenformel | C6H8ClN |
| Durchschnittliche Molmasse | 129,59 g/mol |
| Monoisotopische Masse | 129,034527 g/mol |
| SMILES | Cl.Nc1ccccc1 |
| InChIKey | MMCPOSDMTGQNKG-UHFFFAOYSA-N |
| PubChem CID | 8870 |
| ChEMBL | CHEMBL3182415 |
| EC No. | 205-519-8 |
| DTXSID | DTXSID3020091 |
| Lokaler Name | Aniliniumchlorid |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 26 |
|---|---|
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 8 |
| Formalladung | 0 |
| Komplexität | 46 |
| Dichte | 1.2215 (NTP, 1992) - Denser than waterwill sink1.22 g/cm³ |
| Löslichkeit | less than 1 mg/mL at 64 °F (NTP, 1992)Solubility in water, g/100ml at 20 °C: 1071070g/l1070 g/L (25 ºC) |
| Flammpunkt | 380 °F (NTP, 1992)193 °C o.c. |
| Siedepunkt | 473 °F at 760 mmHg (NTP, 1992)245 °C |
| Schmelzpunkt | 388 °F (NTP, 1992)196-202 °C196-198 °C(lit.) |
| Dampfdichte | 4.46 (NTP, 1992) - Heavier than airwill sink (Relative to Air)Relative vapor density (air = 1): 4.464.46 (vs air) |
| Physical Description | Aniline hydrochloride appears as a white to greenish colored crystalline solid. Toxic by ingestion and a skin and eye irritant. May emit toxic aniline and chloride fumes under exposure to high temperatures or flame. Used to make dyes and printing ink.White hygroscopic solidDarkens on exposure to air and light[ICSC] White to greenish solid[CAMEO] White or black solid[NTP] Off-white crystalline powder with a weak odor[Alfa Aesar MSDS]HYGROSCOPIC WHITE CRYSTALS. TURNS DARK ON EXPOSURE TO AIR AND LIGHT. |
| Brechungsindex | 1.5330 (estimate) |
| Lagerbedingungen | Store below +30°C. |
| Aggregatzustand | Powder |
| Farbe | White to pale yellow-cream |
| Merck | 14,659 |
| BRN | 3593823 |
| Stabilität | Stable. Incompatible with strong oxidizing agents, strong acids. |
| InChI | 1S/C6H7N.ClH/c7-6-4-2-1-3-5-6/h1-5H,7H21H |
| InChIKey | MMCPOSDMTGQNKG-UHFFFAOYSA-N |
| SMILES | Cl.Nc1ccccc1 |
| CAS Datenbank | 142-04-1(CAS DataBase Reference) |
| NIST chemische Informationen | Benzenamine, hydrochloride(142-04-1) |
| EPA chemische Informationen | Aniline hydrochloride (142-04-1) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH301 (98.1%): Toxic if swallowed [Danger Acute toxicity, oral]H311 (98.1%): Toxic in contact with skin [Danger Acute toxicity, dermal]H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]H318 (98.1%): Causes serious eye damage [Danger Serious eye damage/eye irritation]H331 (98.1%): Toxic if inhaled [Danger Acute toxicity, inhalation]H341 (98.1%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]H351 (100%): Suspected of causing cancer [Warning Carcinogenicity]H372 (100%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]H400 (98.1%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]P203, P260, P261, P262, P264, P264+P265, P270, P271, P272, P273, P280, P301+P316, P302+P352, P304+P340, P305+P354+P338, P316, P317, P318, P319, P321, P330, P333+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 52 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Regulatorische Informationen | Chemical: Benzenamine, hydrochlorideHazard Traits - CarcinogenicityAuthoritative List - IARC Carcinogens - 2AProp 65Report - regardless of intended function of ingredient in the productAnilinium chloride: Does not have an individual approval but may be used under an appropriate group standardThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| Weitere Sicherheitsinformationen | Evaluation - Aniline and its salts |
Anwendungen & Verwendung
Beschreibung
Aniline (hydrochloride) (Item No. 21963) is an analytical reference standard that is structurally categorized as a synthetic intermediate. It is used to make the imine derivative of NPP as part of the synthesis of fentanyl (Item Nos. 14719 | ISO60197 ) and its derivatives. This product is intended for research and forensic applications.
Verwenden
Aniline hydrochloride was used in the preparation of polyaniline coated poly(styrene-co-styrene sulfonate) nanoparticles. It was used to study the induction of Nei-like DNA glycosylases (NEIL1/2)-mediated base excision repair(BER) in rat spleen and 8-oxoguanine glycosylase 1-mediated BER due to aniline exposure. It is used in printing inks, clothing marking inks, paints and paint removers. It is also used as a stove polisher and shoe polisher, as well as in the synthesis of dyes, crayons and antioxidants.