Grundinformationen
- Standard-SMILES
CCCCCCCCCCCC(=O)NCCO- InChIKey
QZXSMBBFBXPQHI-UHFFFAOYSA-N- Summenformel
- C14H29NO2
- Durchschnittliche Molmasse
- 243,39 g/mol
- Monoisotopische Masse
- 243,21982917
Namen und Bezeichner
- Bevorzugter Name
- Lauric acid monoethanolamide
- IUPAC
- N-(2-hydroxyethyl)dodecanamide
- Lokaler Name
- N-(2-Hydroxyethyl)dodecanamid
- Englischer Name
- Lauric acid monoethanolamide
- Summenformel
- C14H29NO2
- Molmasse
- 243.39
Namen und Synonyme
Weitere Namen anzeigen
Datenbank-Bezeichner
- CAS
142-78-9- PubChem CID
- 8899
- DTXSID
DTXSID5025493- ChEMBL
CHEMBL246914- ChEBI
CHEBI:85263- UNII
- 098P2IGT76
- EC Number
- 205-560-1
- Nikkaji
- J103.087F
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 4
- Polarare Oberfläche (TPSA)
- 49,3 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 2
- Frei drehbare Bindungen
- 12
- Schwere Atome
- 17
- Formalladung
- 0
- Komplexität
- 172
Experimentelle und physikochemische Eigenschaften
Physical Description
Lauryl ethanolamide is a cream-colored flakes. (NTP, 1992)
Liquid; Other Solid
Cream-colored solid; [CAMEO]
Physikochemische Eigenschaften
- Schmelzpunkt
- 88 · 88-89℃
- Siedepunkt
- 410.7 · 410.7±28.0 °C(Predicted)
- Dichte
- 0.925 · 0.925
- Dampfdruck
- 0.009 Pa · 0.009Pa at 25℃
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 14.49 · 14.49±0.10(Predicted)
- Wasserlöslichkeit
- 11.4 mg/L · 11.4mg/L at 20℃
- Kosmetik-Inhaltsstoffe Funktionen
- VISCOSITY CONTROLLINGSURFACTANT - FOAM BOOSTINGANTISTATICSURFACTANT - CLEANSING
- InChI
- InChI=1S/C14H29NO2/c1-2-3-4-5-6-7-8-9-10-11-14(17)15-12-13-16/h16H,2-13H2,1H3,(H,15,17)
- InChIKey
- QZXSMBBFBXPQHI-UHFFFAOYSA-N
- SMILES
- C(NCCO)(=O)CCCCCCCCCCC
- LogP
- 3.8 at · 3.8 at 20℃
- EPA chemische Informationen
- Lauryl ethanolamide (142-78-9)
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
Danger
H318 (76.4%): Causes serious eye damage [Danger Serious eye damage/eye irritation];H319 (23.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H411 (23.3%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
P264+P265, P273, P280, P305+P351+P338, P305+P354+P338, P317, P337+P317, P391, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 649 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Gefahrenhinweise
Regulatory Information
Chemical: Dodecanamide, N-(2-hydroxyethyl)-
Dodecanamide, N-(2-hydroxyethyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Dodecanamide, N-(2-hydroxyethyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 23-04-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/25660;Status: Active Update: 27-12-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/21833
Laurylethanolamide: Does not have an individual approval but may be used under an appropriate group standard
Reactivity Profile
LAURYL ETHANOLAMIDE is a very weak base. Reacts with azo and diazo compounds to generate toxic gases. Flammable gases are formed with strong reducing agents. Reacts with dehydrating agents such as P2O5 or SOCl2. Combustion generates mixed oxides of nitrogen.
Sicherheit und Schutzausrüstung
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.;SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.;INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.;INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
Nonfire Spill Response
SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.;STORAGE PRECAUTIONS: You should store this material in a refrigerator. (NTP, 1992)
Personal Protective Equipment (PPE)
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)
Toxikologische Informationen
Toxicity Summary
The CIR Expert Panel concluded that the ethanolamides listed subsequently are safe in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating. The Expert Panel cautioned that these ingredients should not be used in cosmetic products in which N-nitroso compounds may be formed...Lauramide MEA...
Safe for use in cosmetics, with qualifications
Non-Human Toxicity Excerpts
Lauryl ethanolamide (LE) was tested for mutagenicity in the Salmonella/microsome preincubation assay using a protocol approved by the National Toxicology Program. LE was tested over a wide range of doses (0, 3.0, 10, 33, 100, 333, 1000, and 3333 ug/plate) in four Salmonella typhimurium strains (TA98, TA100, TA1535, and TA1537) in the presence and absence of Aroclor-induced rat or hamster liver S9. LE was negative in these tests and the highest ineffective dose level tested (not causing the formation of a precipitate) in any Salmonella tester strain was 100 ug/plate.
Regulatorische Informationen
Regulatory Information
Chemical: Dodecanamide, N-(2-hydroxyethyl)-
Dodecanamide, N-(2-hydroxyethyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Dodecanamide, N-(2-hydroxyethyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 23-04-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/25660;Status: Active Update: 27-12-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/21833
Laurylethanolamide: Does not have an individual approval but may be used under an appropriate group standard
Sicherheitsdaten
- tsca
- TSCA listed
- Giftige Stoffe Daten
- 142-78-9(Hazardous Substances Data)
Chemie und Industrie
Verwendung und Herstellung
Uses
CIR ingredient: Lauramide MEA
Ultrapoles is the trademark for several alkanolamine condensates that are surface-active agents; Ultrapoles are used as detergents and in detergents, wetting and foaming agents, foam stabilizers, cosmetic preparations, emollients, and thickening agents; [HSDB]
General Manufacturing Information
Soap, Cleaning Compound, and Toilet Preparation Manufacturing
Dodecanamide, N-(2-hydroxyethyl)-: ACTIVE
ULTRAPOLES /IS/ TRADE MARK FOR SERIES OF ALKANOLAMINE CONDENSATES, DETERGENT BASE & SURFACE ACTIVE MATERIALS USED AS DETERGENTS & INGREDIENTS OF DETERGENTS, WETTING & FOAMING AGENTS, FOAM STABILIZERS, INGREDIENTS FOR COSMETIC PREPN, EMOLLIENTS, THICKENING AGENTS. /ULTRAPOLES/
Vor- und nachgelagerte Produkte
Nachgelagerte Produkte
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Ergänzende Hinweise
DefinitionChEBI: An N-(long-chain-acyl)ethanolamine resulting from the formal condensation of the carboxy group of dodecanoic acid (myristic acid) with the amino group of ethanolamine.
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