HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Nicotine
Identifikatoren & physikalische Daten
| CAS No. | 22083-74-5 |
|---|---|
| Summenformel | C10H14N2 |
| Durchschnittliche Molmasse | 162,23 g/mol |
| Monoisotopische Masse | 162,11569845 g/mol |
| SMILES | CN1CCC[C@H]1c1cccnc1 |
| InChIKey | SNICXCGAKADSCV-JTQLQIEISA-N |
| PubChem CID | 89594 |
| ChEMBL | CHEMBL3 |
| ChEBI | CHEBI:17688 |
| EC No. | 200-193-3 |
| DTXSID | DTXSID1020930 |
Chemische & physikalische Eigenschaften
| XLogP | 1,2 |
|---|---|
| Polarare Oberfläche (TPSA) | 16,1 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 12 |
| Formalladung | 0 |
| Komplexität | 147 |
| Stoffklassen | Biological Agents -> Plant ToxinsTeratogensStimulant-> NIOSH Emergency Response CategoriesPharmaceutical |
| Arzneimittel | Pharmaceuticals -> Listed in ZINC15 |
| Kosmetika | Cosmetics ingredient -> Fragrance |
| pH | pH = 10.2 (0.05 Molar solution) |
| Pestizide | InsecticidesActive substance -> EU Pesticides database: Not approved |
| LogP (Verteilungskoeffizient) | log Kow = 1.170.28 (pH-dependent) |
| Geruch | Fish-like odor when warm |
| Geschmack | Acrid, burning |
| Dichte | 1.0097 at 68 °F (EPA, 1998) - Denser than waterwill sink1.00925 at 20 °C/4 °CRelative density (water = 1): 1.011.0092 @ 20°C |
| Viscosity | Becomes viscous on exposure to air |
| Color/Form | Colorless to pale yellow, oily liquidThick, water-white, levarotatory oil turning brown on exposure to airPale-yellow to dark brown liquid |
| Löslichkeit | Miscible (NTP, 1992)Miscible with water below 60 °Cvery sol in alcohol, chloroform, ether, petroleum ether, kerosene, oilsSlightly soluble in ligroinIn water, 1X10+6 mg/L at 25 °C (miscible)1000 mg/mL |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH300: Fatal if swallowed [Danger Acute toxicity, oral]P260, P262, P264, P270, P271, P273, P280, P284, P301+P316, P302+P352, P304+P340, P316, P320, P321, P330, P361+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)H300 (68%): Fatal if swallowed [Danger Acute toxicity, oral]P260, P262, P264, P264+P265, P270, P271, P273, P280, P284, P301+P316, P302+P352, P304+P340, P305+P354+P338, P316, P317, P320, P321, P330, P332+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement) |
|---|---|
| Regulatorische Informationen | Chemical: Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)-Hazard Traits - CarcinogenicityCardiovascular ToxicityDevelopmental ToxicityRespiratory ToxicityRegulation (EC) No 396/2005 (amended)Status: Active Update: 04-04-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/15857Nicotine: Does not have an individual approval but may be used under an appropriate group standardThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| Weitere Sicherheitsinformationen | - Indoor Air: Nicotine can be released into indoor air as a fine powder or liquid spray (aerosol). |
| DOT-Kennzeichnung | Poison |
| Brandgefahren | There is a moderate explosion hazard when exposed to heat or flame. When heated to decomposition, it emits nitrogen oxides, carbon monoxide and other highly toxic fumes. Avoid oxidizing materials. Stable under normal conditions. Avoid heat or flames. (EPA, 1998)· Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.Combustible under specific conditions. Gives off irritating or toxic fumes (or gases) in a fire. Above 111 °C explosive vapour/air mixtures may be formed. |
| Brandpotenzial | COMBUSTIBLE WHEN EXPOSED TO HEAT OR FLAME. |
| Gesundheitsgefahren |