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Chymopapain
EC 3.4.22.6 · CHYMOPAPAIN · e.c.3.4.4.11 · CHYMOPAPAIN USP/EP/BP · Chymopapain from Papaya · chymopapain from papaya latex · CHYMOPAPAIN FROM PAPAYA LATEXPARTIALLY P URIFIED
Identifikatoren & physikalische Daten
| CAS No. | 149-45-1 |
|---|---|
| Summenformel | C6H6O8S2 |
| Durchschnittliche Molmasse | 270,2 g/mol |
| Monoisotopische Masse | 269,95040949 g/mol |
| SMILES | O=S(=O)(O)c1cc(O)c(O)c(S(=O)(=O)O)c1 |
| InChIKey | XXAXVMUWHZHZMJ-UHFFFAOYSA-N |
| PubChem CID | 9002 |
| ChEMBL | CHEMBL1205542 |
| ChEBI | CHEBI:193860 |
| EC No. | 205-741-5 |
| DTXSID | DTXSID6043963 |
| Lokaler Name | Chymopapain |
Chemische & physikalische Eigenschaften
| XLogP | -0,7 |
|---|---|
| Polarare Oberfläche (TPSA) | 166 |
| H-Brücken-Donoren | 4 |
| H-Brücken-Akzeptoren | 8 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 16 |
| Formalladung | 0 |
| Komplexität | 440 |
| Collision Cross Section | 145.8 Ų [M-H]- [CCS Type: DTBuffer gas: N2Ionization: ESI-Dataset: TOXCASTSource Identifier: DTXSID7043950] |
| Lagerbedingungen | -20°C |
| Aggregatzustand | lyophilized powder |
| Farbe | White to off-white |
| Löslichkeit | H2O: soluble 5.0mg/mL, clear, colorless |
| Merck | 13,2281 |
| Specific Activity | ≥2.0units/mg protein |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (88.2%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 51 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Chemical: 1,3-Benzenedisulfonic acid, 4,5-dihydroxy-REACH registered substance: Disodium 4,5-dihydroxybenzene-1,3-disulphonate (EC: 205-741-5) |
| Hazard Classes and Categories | Skin Irrit. 2 (88.2%) |
| RTECS-Nr. | GC2800000 |
| R-Sätze (R) | 36/37/38-42/43 |
| Gefahrensymbole | Xn |
| Sicherheitshinweise (S) | 23-26-36/37-45 |
Anwendungen & Verwendung
Verwenden
Chymopapain from papaya latex has been used in a study to assess the anthelmintic effect of natural plant cysteine proteinases against the gastrointestinal nematode, Heligmosomoides. Chymopapain from papaya latex has also been used in a study to investigate the preparation and identification of the rabbit′s antibody of chymopapain.