Taurohyodeoxycholic acid sodium salt hydrate
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Grundinformationen
- CAS
38411-85-7- Standard-SMILES
C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3C[C@H](O)[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C.[Na+]- InChIKey
VNQXUJQHLHHTRC-WMWRQJSFSA-M- Summenformel
- C26H46NNaO6S
- Durchschnittliche Molmasse
- 523,7 g/mol
Namen und Bezeichner
- Bevorzugter Name
- Taurohyodeoxycholic acid sodium salt hydrate
- Englischer Name
- Taurohyodeoxycholic acid sodium salt hydrate
- Summenformel
- C26H46NNaO6S
- Molmasse
- 523.7
Namen und Synonyme
Taurine pig deoxycholate sodiumSodium taurocholic acid deoxycholateTaurohyodeoxycholic acid sodium salt hydrateTaurohyodeoxycholic acid sodium salt (Standard)Taurohyodeoxycholic acid hydrate sodium saltTaurohyodeoxycholic acid sodium salt, 10 mM in DMSO5β-CHOLANIC ACID-3α, 6α-DIOL N-(2-SULPHOETHYL)-AMIDESodium taurohyodeoxycholate hydrate,Taurohyodeoxycholic acid sodium salt hydrate
Datenbank-Bezeichner
- CAS
38411-85-7- PubChem CID
- 90478527
- UNII
- 4N9535CHEK
Eigenschaften
Physikochemische Eigenschaften
- storage temp.
- -20 °C · Store at -20°C
- Löslichkeit
- 30 mg/ml,DMF:PBS · DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml
- Aggregatzustand
- A crystalline solid
- Farbe
- White to off-white
- InChIKey
- VNQXUJQHLHHTRC-WMWRQJSFSA-M
- SMILES
- [Na+].[S](=O)(=O)([O-])CCNC(=O)CC[C@H]([C@@H]1[C@@]2([C@H]([C@H]3[C@@H]([C@@]4([C@H]([C@H](C3)O)C[C@@H](CC4)O)C)CC2)CC1)C)C
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
Sicherheitsdaten
- wgk
- 3
- Speicherklasse
- 11 - Combustible Solids
Chemie und Industrie
Anwendungen
BeschreibungTaurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid . THDCA decreases the size and weight of human gallstones in vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats. Co-administration of THDCA with taurochenodeoxycholic acid (TCDCA; ) prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats. THDCA also reduces myeloperoxidase activity, expression of TNF-α and IL-6, and colonic damage in a mouse model of TNBS-induced ulcerative colitis.
VerwendenSodium taurohyodeoxycholate hydrate has been used in a study to assess dose-response data for cytotoxicity, regenerative cell proliferation and secondary oxidative DNA damage in rat livers treated with furan. It has also been used in a study to investigate the use of an immobilized artificial membrane HPLC column to predict bile salt-membrane interactions.
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湖南韵邦生物科技股份有限公司0731-88532326 13319508186 · [email protected]
南通飞宇生物科技有限公司0513-68819626 15152877458 · [email protected]
Shaanxi LonierHerb Bio Technology Co Ltd+86-86-+86-86-029-87551862 15002946897 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
成都彼样生物科技有限公司18108052721 · [email protected]
普善实业（陕西）有限公司029-81310890 18165209495 · [email protected]
苏州市森菲达化工有限公司18796480002 18796480002 · [email protected]
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