Tecovirimat monohydrate

HCID 90479083
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Grundinformationen

CAS
1162664-19-8
Standard-SMILES
O.O=C(NN1C(=O)[C@@H]2[C@@H]3C=C[C@@H]([C@H]4C[C@@H]34)[C@@H]2C1=O)c1ccc(C(F)(F)F)cc1
InChIKey
QRHXYGPOQKLBJP-NPIFKJBVSA-N
Summenformel
C19H17F3N2O4
Durchschnittliche Molmasse
394,3 g/mol

Überblick

Tecovirimat is an antiviral prescription medicine approved by the U.S. Food and Drug Administration(FDA) for the treatment of smallpox in adults and children. (Smallpox is a disease caused by the variola virus, a member of a group of viruses called Orthopoxvirus. Since 1980, smallpox has been considered eradicated worldwide.)

Namen und Bezeichner

Bevorzugter Name
Tecovirimat monohydrate
IUPAC
N-[(1R,2R,6S,7S,8S,10R)-3,5-dioxo-4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-en-4-yl]-4-(trifluoromethyl)benzamide;hydrate

Namen und Synonyme

Tecovirimat monohydrateST-246 monohydrate1162664-19-8SB96YO2BR8Benzamide, N-((3aR,4R,4aR,5aS,6S,6aS)-3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop(F)isoindol-2(1H)-yl)-4-(trifluoromethyl)-, hydrate (1:1), rel-RefChem:58027Tecovirimat monohydrate [MI]UNII-SB96YO2BR8Tecovirimat hydrateTecovirimat (monohydrate)ST246 hyrateorb2702726
Weitere Namen anzeigen
CHEMBL5315121SCHEMBL30702765GLXC-21217HY-14805AAKOS040742701Tecovirimat Monohydrate - API StandardsTECOVIRIMAT MONOHYDRATE [WHO-DD]CS-0066577

Datenbank-Bezeichner

CAS
1162664-19-8
PubChem CID
90479083
ChEMBL
CHEMBL5315121
UNII
SB96YO2BR8

Eigenschaften

Berechnete StruktureigenschaftenWird ergänzt

Polarare Oberfläche (TPSA)
67,5 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
7
Frei drehbare Bindungen
1
Schwere Atome
28

Experimentelle und physikochemische Eigenschaften

Human DrugsEMA approved medicines: Human medicine

Chemie und Industrie

Pharmakologische Informationen

FDA Pharmacological Classification · 2 Einträge

TECOVIRIMAT MONOHYDRATE

Cytochrome P450 3A Inducers [MoA]; Cytochrome P450 2C8 Inhibitors [MoA]; Orthopoxvirus VP37 Envelope Wrapping Protein Inhibitor [EPC]; Cytochrome P450 2C19 Inhibitors [MoA]; Breast Cancer Resistance Protein Inhibitors [MoA]

MeSH Pharmacological Classification · 1 Eintrag

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.

Anbieter13 Anbieter

山东科立康药业有限公司053-88113608 17854192669
Hebei Zhuanglai Chemical Trading Co Ltd+86-16264648883 · [email protected]
武汉敬康恩生物医药科技有限公司13720134139 086-15871494362 13720134139 · [email protected]
浙江珲达生物科技有限公司0571-89903022 18679456698 · [email protected]
NANJING YINGWEN BIOTECHNOLOGY CO LTD+86-13382787392 · [email protected]

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