Dibenzo[def,mno]chrysen

This chemical does not meet GHS hazard criteria for 5.6% (3 of 54) of reports.

Danger

H315 (72.2%): Causes skin irritation [Warning Skin corrosion/irritation]

P203, P264, P280, P302+P352, P318, P321, P332+P317, P362+P364, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 54 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

PAH metabolism occurs in all tissues, usually by cytochrome P-450 and its associated enzymes. PAHs are metabolized into reactive intermediates, which include epoxide intermediates, dihydrodiols, phenols, quinones, and their various combinations. The phenols, quinones, and dihydrodiols can all be conjugated to glucuronides and sulfate esters; the quinones also form glutathione conjugates. (L10)

Used as a research chemical; Present in fossil fuels, coal tar, cigarette smoke, coal smoke, gasoline engine exhaust, high-protein foods, barbecue smoke, charcoal-broiled meats, vegetable oils and fats, sewage sludge, dried lake sediments, various lubricating oils, used motor oils, and urban air; [CHEMINFO]

PAHs are released into the environment via the combustion of fossil fuels, coke oven emissions and vehicle exhausts, as well as naturally from forest fires and vocanic eruptions. PAHs from these sources may contaminate nearly water systems. They are also found in coal tar and charbroiled food. (L10)