Fenfluramine Hydrochloride

HCID 91452CAS 16105-77-4
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Grundinformationen

Standard-SMILES
CCNC(C)Cc1cccc(C(F)(F)F)c1.Cl
InChIKey
ZXKXJHAOUFHNAS-UHFFFAOYSA-N
Summenformel
C12H17ClF3N
Durchschnittliche Molmasse
267,72 g/mol
Monoisotopische Masse
267,10016188

Überblick

Fenfluramine Hydrochloride is the hydrochloride salt of fenfluramine, an amphetamine derivative and a sympathomimetic stimulant with appetite-suppressant properties. Fenfluramine, which was part of the Fen-Phen anti-obesity medication, stimulates the release of serotonin from vesicular storage, and modulates serotonin transporter function. Since serotonin regulates mood and appetite, among other functions, increased serotonin level results in a feeling of fullness and loss of appetite.

Namen und Bezeichner

Bevorzugter Name
Fenfluramine Hydrochloride
IUPAC
N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine;hydrochloride
Englischer Name
Fenfluramine hydrochloride
Summenformel
C12H17ClF3N
Molmasse
267.72

Namen und Synonyme

Fenfluramine hydrochlorideFenfluramine HClGanal404-82-0PondiminPonderax pacapsAHR-3002HHR-9651-(3-Trifluoromethylphenyl)-2-ethylaminopropane hydrochloride3KC089243PN-Ethyl-alpha-methyl-m-(trifluoromethyl)phenethylamine hydrochlorideDTXSID30936444
Weitere Namen anzeigen
(+-)-fenfluraminechlorideFEBFLURAMINE HYDROCHLORIDEZXKXJHAOUFHNAS-UHFFFAOYSA-Ndl-fenfluraminehydrochlorideracemicfenfluraminehydrochloride(±)-Fenfluramine hydrochloride solution(±)-Fenfluramine solution hydrochloridefenfluramine hydrochloride*methanol solutionFENFLURAMINE HYDROCHLORIDE--DEA*SCHEDULE IV ITEM
Benzeneethanamine, N-ethyl-alpha-methyl-3-(trifluoromethyl)-, hydrochlorideCHEBI:59729RefChem:56386DTXCID901365052206-968-2dl-Fenfluramine hydrochloride16105-77-4Racemic fenfluramine hydrochloride

Datenbank-Bezeichner

CAS
16105-77-4、404-82-0
PubChem CID
91452
DTXSID
DTXSID30936444
ChEMBL
CHEMBL2106217
UNII
3KC089243P
EC Number
206-968-2、623-877-7

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
12 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
4
Frei drehbare Bindungen
4
Schwere Atome
17

Experimentelle und physikochemische Eigenschaften

Human Drugs · 3 Einträge

FDA approved drugs -> Active ingredient

EMA approved medicines: Human medicine (Orphan designations)

FDA approved drugs -> Active ingredient

Physikochemische Eigenschaften

Schmelzpunkt
166 C · 166 C
Flammpunkt
11 °C · 11 °C
storage temp.
2 · 2-8°C

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

Danger

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 41 reports by companies from 2 notifications to the ECHA C&L Inventory.

Danger

H300 (50%): Fatal if swallowed [Danger Acute toxicity, oral]

Gefahrenhinweise

Regulatory InformationBenzeneethanamine, N-ethyl-.alpha.-methyl-3-(trifluoromethyl)-, hydrochloride: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Benzeneethanamine, N-ethyl-.alpha.-methyl-3-(trifluoromethyl)-, hydrochloride: Human health tier I assessment
Hazard Classes and Categories · 2 Einträge

Acute Tox. 2 (50%)

Acute Tox. 3 (100%)

Sicherheitsdaten

wgk
3
ridadr
UN 2811 6.1/PG 3
RTECS-Nr.
DA0295500
risk_code
25-39/23/24/25-23/24/25-11-36/37/38
hazard_code
T,F,Xi
safety_code
7-16-36/37-45-28-22-36-26

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological Classification · 2 Einträge

Drugs used for their effects on serotonergic systems. Among these are drugs that affect serotonin receptors, the life cycle of serotonin, and the survival of serotonergic neurons.

Compounds that specifically inhibit the reuptake of serotonin in the brain.

Anbieter3 Anbieter

杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
Zhejiang J&C Biological Technology Co.,Limited+1-2135480471 · [email protected]
Alchem Pharmtech,Inc.8485655694 · [email protected]

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