Flumethrin

Danger

H300 (34.7%): Fatal if swallowed [Danger Acute toxicity, oral]；H301 (65.3%): Toxic if swallowed [Danger Acute toxicity, oral]；H310 (34.7%): Fatal in contact with skin [Danger Acute toxicity, dermal]；H311 (41.6%): Toxic in contact with skin [Danger Acute toxicity, dermal]；H315 (41.6%): Causes skin irritation [Warning Skin corrosion/irritation]；H317 (41.6%): May cause an allergic skin reaction [Warning Sensitization, Skin]；H319 (76.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H330 (26.7%): Fatal if inhaled [Danger Acute toxicity, inhalation]；H331 (38.6%): Toxic if inhaled [Danger Acute toxicity, inhalation]；H335 (23.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]；H360 (34.7%): May damage fertility or the unborn child [Danger Reproductive toxicity]；H370 (34.7%): Causes damage to organs [Danger Specific target organ toxicity, single exposure]；H372 (34.7%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]；H400 (23.8%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]；H410 (58.4%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P203, P260, P261, P262, P264, P264+P265, P270, P271, P272, P273, P280, P284, P301+P316, P302+P352, P304+P340, P305+P351+P338, P308+P316, P316, P318, P319, P320, P321, P330, P332+P317, P333+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 101 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

The highest concentration is found in the liver, but high concentrations were also found in the spleen, kidney, lung, adrenal cortex, cartilage, bone marrow, pineal gland, pituitary, and subcutaneous adipose tissue; the lowest concentrations are found in the central nervous system. Flumethrin is excreted in the urine or the feces as unchanged compound or the metabolite, 3-[2-chloro-2-(4-chlorophenyl)ethenyl]-2,2-dimethylcyclopropanecarboxylic acid, flumethrin acid. 3-(4'-hydroxy-phenoxy)-4-fluorobenzoic acid and 3-phenoxy-4-fluorobenzoic acid can further be found in the urine as well as their glycine conjugates. The phenyl ring may be hydroxylated and, following ester bond hydrolysis, the cyano group is converted to SCN- and carbon dioxide and 3-phenoxybenzaldehyde is oxidized to the carboxylic acid. The resultant acids and phenols can then conjugate with glucuronic acid, sulfate, and/or amino acids. (L885)