Bis(2-ethylhexyl)hydrogenphosphat

Fire Extinguishing Agents Not to Be Used: Water or foam may cause frothing.

Use water spray, powder, alcohol-resistant foam, carbon dioxide.

Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Do NOT induce vomiting. Refer for medical attention .

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

Personal protection: chemical protection suit including self-contained breathing apparatus. Collect leaking liquid in covered dry plastic containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Quality assurance to ascertain the completeness of the cleaning procedures should be implemented before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at end of shift, but should remain at employee's place of work for cleaning.

LC50 Danio rerio (Zebra danio) >56 mg/L/96 hr; static /formulated product/

LC50 Daphnia magna (Water flea) >42 mg/L/24 hr; static /formulated product/

LC50 Daphnia magna (Water flea) >42 mg/L/48 hr; static /formulated product/

LC50 Daphnia magna (Water flea) 46.8 mg/L/72 hr (95% confidence limit: 19.8-110.0); static /formulated product/

For more Ecotoxicity Values (Complete) data for BIS(2-ETHYLHEXYL) PHOSPHATE (7 total), please visit the HSDB record page.

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 1.7X10+4(SRC), determined from a structure estimation method(2), indicates that bis(2-ethylhexyl) phosphate is expected to be immobile in soil(SRC). The estimated pKa of bis(2-ethylhexyl) phosphate is 1.47(3), indicating that this compound will primarily exist in anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(4). Volatilization of bis(2-ethylhexyl) phosphate from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 4.1X10-8 atm-cu m/mole(SRC), using a fragment constant estimation method(5). Bis(2-ethylhexyl) phosphate is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 4.7X10-8 mm Hg(SRC), determined from a fragment constant method(6). Bis(2-ethylhexyl) phosphate, present at 100 mg/L, reached 0-17% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/L and the Japanese MITI test(7) and therefore this compound may not biodegrade rapidly in terrestrial environments(SRC).

AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 1.7X10+4(SRC), determined from a structure estimation method(2), indicates that bis(2-ethylhexyl) phosphate is expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 4.1X10-8 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). The estimated pKa of bis(2-ethylhexyl) phosphate is 1.47(5), indicating that this compound will primarily exist in anion form in the environment and anions generally do not adsorb more strongly to organic carbon than their neutral counterparts(6). The sorption of organophosphorus compounds in soil depends on both organic matter and clay content of soil and the sorption increases as the pH of soil decreases(7). In a study on the sorption of bis(2-ethylhexyl) phosphate on kaolinite and amectite, the acidic phosphoric group reacted rapidly and almost irreversibly with the surface cations of the clay mineral structure(7), therefore, adsorption to suspended solids and sediments is expected to be pH dependent. According to a classification scheme(8), measured BCF values of 1-2.4 and 2.7-6.0(9) suggest the potential for bioconcentration in aquatic organisms is low(SRC). Bis(2-ethylhexyl) phosphate, present at 100 mg/L, reached 0-17% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/L and the Japanese MITI test(9) and therefore this compound is not expected to biodegrade rapidly in aquatic environments(SRC).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), bis(2-ethylhexyl) phosphate, which has an estimated vapor pressure of 4.7X10-8 mm Hg at 25 °C(SRC), determined from a fragment constant method(2), is expected to exist solely in the particulate phase in the ambient atmosphere. Particulate-phase bis(2-ethylhexyl) phosphate may be removed from the air by wet or dry deposition(SRC). Bis(2-ethylhexyl) phosphate does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC).

Burning sensation. Cough. Sore throat.

Redness. Burning sensation. Pain. Blisters.

Redness. Pain. Severe burns.

Using a structure estimation method based on molecular connectivity indices(1), the Koc of bis(2-ethylhexyl) phosphate can be estimated to be 1.7X10+4(SRC). According to a classification scheme(2), this estimated Koc value suggests that bis(2-ethylhexyl) phosphate is expected to be immobile in soil. The estimated pKa of bis(2-ethylhexyl) phosphate is 1.47(3), indicating that this compound will primarily exist in anion form in the environment and anions generally do not adsorb more strongly to organic carbon than their neutral counterparts(4). The sorption of organophosphorus compounds in soil depends on both organic matter and clay content of soil and the sorption increases as the pH of soil decreases(5). In a study on the sorption of bis(2-ethylhexyl) phosphate on kaolinite and amectite, the acidic phosphoric group reacted rapidly and almost irreversibly with the surface cations of the clay mineral structure(5).

/SIGNS AND SYMPTOMS/ Causes smarting of skin and first degree burns on short exposure and may cause second degree burns on long exposure. Irritating to skin and eyes.

/SIGNS AND SYMPTOMS/ Inhalation: Burning sensation. Cough. Sore throat.; Skin: Redness. Burning sensation. Pain. Blisters.; Eyes: Redness. Pain. Severe deep burns.

Bis(2-ethylhexyl) phosphate's production and use as a metal extraction agent, a textile lubricant and antistatic agent, an extreme pressure additive, an intermediate for wetting agents and detergent, and a feedstock for chemical synthesis(1-3) may result in its release to the environment through various waste streams(SRC).

AEROBIC: Bis(2-ethylhexyl) phosphate, present at 100 mg/L, reached 0-17% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/L and the Japanese MITI test(1); therefore, this compound is not expected to biodegrade rapidly(SRC).

BCF values of 1-2.4 and 2.7-6.0 were measured for bis(2-ethylhexyl) phosphate at concentrations of 1 and 0.1 mg/L, respectively, using carp which were exposed over an 6-week period(1). According to a classification scheme(2), these BCF values suggest the potential for bioconcentration in aquatic organisms is low(SRC).

The Henry's Law constant for bis(2-ethylhexyl) phosphate is estimated as 4.1X10-8 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This Henry's Law constant indicates that bis(2-ethylhexyl) phosphate is expected to be essentially nonvolatile from water surfaces(2). Bis(2-ethylhexyl) phosphate's Henry's Law constant indicates that volatilization from moist soil surfaces is not expected to occur(SRC). Bis(2-ethylhexyl) phosphate is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 4.7X10-8 mm Hg(SRC), determined from a fragment constant method(3).

Section 8(a) of TSCA requires manufacturers of this chemical substance to report preliminary assessment information concerned with production, exposure, and use to EPA as cited in the preamble in 51 FR 41329.

Pursuant to section 8(d) of TSCA, EPA promulgated a model Health and Safety Data Reporting Rule. The section 8(d) model rule requires manufacturers, importers, and processors of listed chemical substances and mixtures to submit to EPA copies and lists of unpublished health and safety studies. Bis(2-ethylhexyl)phosphate is included on this list.