Orotidine
Grundinformationen
- CAS
314-50-1- Standard-SMILES
O=C(O)c1cc(=O)[nH]c(=O)n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O- InChIKey
FKCRAVPPBFWEJD-XVFCMESISA-N- Summenformel
- C10H12N2O8
- Durchschnittliche Molmasse
- 288,21 g/mol
- Monoisotopische Masse
- 288,05936535
Überblick
Orotidine is a nucleoside formed by attaching orotic acid to a ribose ring via a betaN(1)-glycosidic bond. It has a role as a plant metabolite, a fungal metabolite and a bacterial metabolite. It is a pyrimidinemonocarboxylic acid, a member of uridines and a nucleoside.
Namen und Bezeichner
- Bevorzugter Name
- Orotidine
- IUPAC
- 3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,6-dioxopyrimidine-4-carboxylic acid
- Englischer Name
- OROTIDINE
- Summenformel
- C10H12N2O8
- Molmasse
- 288.21
Namen und Synonyme
Orotidine314-50-16-Carboxyuridine3-Ribofuranosylorotic acidB350MC02GZ3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,6-dioxopyrimidine-4-carboxylic acidCHEBI:257223-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-2,6-dioxopyrimidine-4-carboxylic acidRefChem:168575Uridine-6-carboxylicacid
Weitere Namen anzeigen
Orotidine ,98%URIDINE-6-CARBOXYLIC ACIDorotidine free acid approx. 90%Orotidine (Uridine-6-carboxylic acid)1,2,3,6-Tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-4-pyrimidinecarboxylic acid4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-
4-Pyrimidinecarboxylicacid, 1,2,3,6-tetrahydro-2,6-dioxo-3-b-D-ribofuranosyl-Uridin-6-carboxylic acidUNII-B350MC02GZ4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-3-ss-D-ribofuranosyl-; Orotidine (6CI,7CI,8CI); 1,2,3,6-Tetrahydro-2,6-dioxo-3-ss-D-ribofuranosyl-4-pyrimidinecarboxylic acid; 6-Carboxyuridine; Orotic acid ribosideOrotic acid ribosideOROTIDINE [MI]1,2,3,6-Tetrahydro-2,6-dioxo-3-beta-D-ribofuranosyl-4-pyrimidinecarboxylic acidSCHEMBL20894
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- -2,6
- Polarare Oberfläche (TPSA)
- 157 Ų
- H-Brücken-Donoren
- 5
- H-Brücken-Akzeptoren
- 8
- Frei drehbare Bindungen
- 3
- Schwere Atome
- 20
- Formalladung
- 0
- Komplexität
- 490
Experimentelle und physikochemische Eigenschaften
Melting Point> 400 °C
Physical DescriptionSolid
Physikochemische Eigenschaften
- Schmelzpunkt
- 400 °C · >400 °C
- Dichte
- 1.847 · 1.847±0.06 g/cm3(Predicted)
- storage temp.
- 20 °C · −20°C
- Löslichkeit
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- Aggregatzustand
- Solid
- pka
- 2.62 · 2.62±0.20(Predicted)
- Farbe
- White to Off-White
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
Sicherheitsdaten
- wgk
- 3
- hs_code
- 29349990
Chemie und Industrie
Pharmakologische Informationen
Tissue LocationsPlacenta
Cellular LocationsCytoplasm
Anwendungen
VerwendenOrotidine is a metabolite of Orotic Acid (O691500); a compound used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment.
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武汉丰泰威远科技有限公司+86-27-8746-5837 +86-18627785180 · [email protected]
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北京秦岭医药科技有限公司010-61241352 18901327973 · [email protected]
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