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Disuccinimidodithiobispropionat
DSP · DTSP · DITHIOBIS(SUCCINIMIDYL PROPIONATE) · DI(N-SUCCINIMIDYL) 3,3'-DITHIODIPROPIONATE · SULFO-DSS · NSC 328386 · LOMANTS REAGENT · DSP Crosslinker
Identifikatoren & physikalische Daten
| CAS No. | 57757-57-0 |
|---|---|
| Summenformel | C14H16N2O8S2 |
| Durchschnittliche Molmasse | 404,4 g/mol |
| Monoisotopische Masse | 404,03480782 g/mol |
| SMILES | O=C(CCSSCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O |
| InChIKey | FXYPGCIGRDZWNR-UHFFFAOYSA-N |
| PubChem CID | 93313 |
| EC No. | 260-931-5 |
| DTXSID | DTXSID00206449 |
| Lokaler Name | Disuccinimidodithiobispropionat |
Chemische & physikalische Eigenschaften
| XLogP | -1,2 |
|---|---|
| Polarare Oberfläche (TPSA) | 178 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 10 |
| Frei drehbare Bindungen | 11 |
| Schwere Atome | 26 |
| Formalladung | 0 |
| Komplexität | 552 |
| Stoffklassen | Other Classes -> Sulfur Compounds |
| Physical Description | White powder[Sigma-Aldrich MSDS] |
| Schmelzpunkt | 128-133 °C |
| Siedepunkt | 560.1±60.0 °C(Predicted) |
| Dichte | 1.57±0.1 g/cm3(Predicted) |
| Lagerbedingungen | -20°C |
| Löslichkeit | chloroform: 50 mg/mL |
| Aggregatzustand | powder |
| Farbe | Off-White |
| BRN | 1518074 |
| InChI | InChI=1S/C14H16N2O8S2/c17-9-1-2-10(18)15(9)23-13(21)5-7-25-26-8-6-14(22)24-16-11(19)3-4-12(16)20/h1-8H2 |
| InChIKey | FXYPGCIGRDZWNR-UHFFFAOYSA-N |
| SMILES | S(CCC(ON1C(=O)CCC1=O)=O)SCCC(ON1C(=O)CCC1=O)=O |
| CAS Datenbank | 57757-57-0(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 42 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Gefahrenübersicht | A skin and strong eye irritantMay cause CNS depression[Sigma-Aldrich MSDS] See 2-Hydroxyethyl disulfide. See Disuccinimidyl oxalate. |
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| F | 10-21 |
| Wassergefährdungsklasse (WGK) | 3 |
| Zollcode | 29309090 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 26-36 |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrenklasse | Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
Anwendungen & Verwendung
Verwenden
3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester) can be used in the crosslinking of intracellular proteins prior to cell lysis.