N-2-Hydroxyethyllactamid

N-(2-hydroxyethyl)lactamide

HCID 95457CAS 5422-34-4
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Grundinformationen

Standard-SMILES
CC(O)C(=O)NCCO
InChIKey
RZCHTMXTKQHYDT-UHFFFAOYSA-N
Summenformel
C5H11NO3
Durchschnittliche Molmasse
133,15 g/mol
Monoisotopische Masse
133,07389321

Überblick

N-Lactoyl ethanolamine is a N-acylethanolamine.

Namen und Bezeichner

Bevorzugter Name
N-(2-hydroxyethyl)lactamide
IUPAC
2-hydroxy-N-(2-hydroxyethyl)propanamide
Lokaler Name
N-2-Hydroxyethyllactamid
Englischer Name
N-(2-Hydroxyethyl)lactamide
Summenformel
C5H11NO3
Molmasse
133.15

Namen und Synonyme

N-(2-Hydroxyethyl)lactamide2-LactamidoethanolRefChem:4733581-hydroxyethane-1-(2'-hydroxyethyl)carbonamide5422-34-42-Hydroxy-N-(2-hydroxyethyl)propanamideLactamide MEAPropanamide, 2-hydroxy-N-(2-hydroxyethyl)-n-lactoyl ethanolamineLactic acid monoethanolamideLactamide, N-(2-hydroxyethyl)-N-2-Hydroxyethyllactamide
Weitere Namen anzeigen
MFCD0003Naetex-LAMlactamidemeaMackamide LMESchercomid LMEParapel LAM-100Upamide LACAMEA
MFCD00037805N-HydroxyaethyllactamidCCRIS 3086Lipamide LMEAIncromectant LMEAN-beta-HydroxyethyllactamideNSC 11062Monoethanolamine lactic acid amide

Datenbank-Bezeichner

CAS
5422-34-4
PubChem CID
95457
DTXSID
DTXSID20863533
ChEBI
CHEBI:173359
UNII
900T44YNC7
EC Number
226-546-1
Nikkaji
J60.793B

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-1,4
Polarare Oberfläche (TPSA)
69,6 Ų
H-Brücken-Donoren
3
H-Brücken-Akzeptoren
3
Frei drehbare Bindungen
3
Schwere Atome
9

Experimentelle und physikochemische Eigenschaften

Cosmetics · 2 Einträge

Cosmetic ingredients (Lactamide MEA) -> CIR (Cosmetic Ingredient Review)

Skin conditioning; Humectant; Antistatic; Hair conditioning

FragrancesFragrance Ingredient (N-Lactoyl ethanolamine) -> IFRA transparency List
Food AdditivesFLAVORING AGENT OR ADJUVANT -> FDA Substance added to food
Density1.182-1.186
Solubility · 2 Einträge

Very soluble in water; insoluble in pentane and diethyl ether

Slightly soluble (in ethanol)

Boiling Point · 2 Einträge

380.00 °C. @ 760.00 mm Hg

372-380 °C

Physikochemische Eigenschaften

Siedepunkt
380.3 · 380.3±27.0 °C(Predicted)
Dichte
1 · 1,2 g/cm3
Brechungsindex
1.482 to · 1.4820 to 1.4870
FEMA
4256 · 4256 | N-LACTOYL ETHANOLAMINE
storage temp.
Sealed in dry,Room Temperature
Aggregatzustand
clear liquid

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 3 Einträge

This chemical does not meet GHS hazard criteria for 97.3% (1363 of 1401) of all reports.

Not Classified

Aggregated GHS information provided per 1401 reports by companies from 4 notifications to the ECHA C&L Inventory.

Gefahrenhinweise

Regulatory Information · 5 Einträge

Chemical: Propanamide, 2-hydroxy-N-(2-hydroxyethyl)-

Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)

Propanamide, 2-hydroxy-N-(2-hydroxyethyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Propanamide, 2-hydroxy-N-(2-hydroxyethyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 18-07-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/21492

Propanamide, 2-hydroxy-N-(2-hydroxyethyl)-: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesNot Classified

Toxikologische Informationen

Toxicity Summary · 2 Einträge

The CIR Expert Panel concluded that the ethanolamides listed subsequently are safe in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating. The Expert Panel cautioned that these ingredients should not be used in cosmetic products in which N-nitroso compounds may be formed...Lactamide MEA...

Safe for use in cosmetics, with qualifications

Sicherheitsdaten

wgk
WGK 3
tsca
TSCA listed
hs_code
2922.39.5000
RTECS-Nr.
OD2400000
risk_code
36/37/38
safety_code
26-36/37/39

Chemie und Industrie

Pharmakologische Informationen

Cellular LocationsCytoplasm

Verwendung und Herstellung

UsesCIR ingredient: Lactamide MEA
U.S. Production2023: 137,300 lb
Consumer UsesHumectant
Industry UsesProcessing aids not otherwise specified
Household ProductsInformation on 1 consumer products that contain Lactamide Mea in the following categories is provided:
Use Classification · 4 Einträge

Fragrance Ingredients

Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes

Flavoring Agents -> JECFA Flavorings Index

Cosmetics -> Skin conditioning; Humectant; Antistatic; Hair conditioning

Anwendungen

Verwendenlactamide MEA is a surfactant that can also act as a thickener, foam booster, and stabilizer.

Anbieter46 Anbieter

北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
南京世洲生物科技有限公司025-85560043 15850508050 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]

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