873225-46-8O=C(c1ccc(Nc2nccc(-c3cc4ccccc4s3)n2)cc1)N1CCC(N2CCCC2)CC1BWZJBXAPRCVCKQ-UHFFFAOYSA-NIKK16 is a 1-benzothiophene substituted by a 2-{4-[4-(pyrrolidin-1-yl)piperidine-1-carbonyl]anilino}pyrimidin-4-yl group at position 2. It is an IB kinase (IKK) inhibitor. It has a role as an antimalarial, a NF-kappaB inhibitor and an EC 2.7.11.10 (IkappaB kinase) inhibitor. It is a member of benzamides, a member of pyrrolidines, an aminopyrimidine, a member of 1-benzothiophenes, a N-acylpiperidine and a secondary amino compound.
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 38 reports by companies from 1 notifications to the ECHA C&L Inventory.
VerwendenIKK-16 is a potential novel IκB kinase 2 (IKK2) inhibitor used in the treatment of various immune/inflammatory disorders.
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873225-46-8DTXSID80429553CHEMBL200027CHEBI:92257