Dichlorotrimethylantimon

Nsc140285 · Trimethyldichlorostibine · Trimethyldichloroantimony · Dichlorotrimethylantimony · Antimony,dichlorotrimethyl- · Antimony, dichlorotrimethyl- · Trimethyldichloroantimony(V) · Dichlorotrimethylantimony(V)

https://huagongshe.com/de/chemical/97653

Molekülstruktur von Dichlorotrimethylantimon

Identifikatoren & physikalische Daten

CAS No.	13059-67-1
Summenformel	C3H9Cl2Sb
Durchschnittliche Molmasse	237,77 g/mol
Monoisotopische Masse	235,91194 g/mol
SMILES	[CH3][Sb]([CH3])([CH3])([Cl])[Cl]
InChIKey	IEOZXTYTNPKDKQ-UHFFFAOYSA-L
PubChem CID	97653
EC No.	235-952-8
DTXSID	DTXSID80156630
Lokaler Name	Dichlorotrimethylantimon

Chemische & physikalische Eigenschaften

Polarare Oberfläche (TPSA)	0
H-Brücken-Donoren	0
H-Brücken-Akzeptoren	0
Frei drehbare Bindungen	0
Schwere Atome	6
Formalladung	0
Komplexität	54,9
Schmelzpunkt	222-223 °C (dec.)(lit.)

Sicherheit & Vorschriften

Carcinogen Classification
Treatment	Following oral exposure to antimony, administer charcoal as a slurry (240 mL water/30 g charcoal). Following inhalation exposure, move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids. In case of eye exposure, irrigate exposed eyes with copious amounts of room temperature water for at least 15 minutes. Following dermal exposure, Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician may need to examine the area if irritation or pain persists. (T36)
Gesundheitliche Auswirkungen	Dermal exposure to antimony can cause antimony spots (papules and pustules around sweat and sebaceous glands). Antimony poisoning can also lead to pneumoconiosis. Alterations in pulmonary function and other effects including chronic bronchitis, chronic emphysema, inactive tuberculosis, pleural adhesions, and irritation can result from inhalation of antimony. Increased blood pressure can also result from antimony poisoning. Myocardial depression, vasodilation and fluid loss may cause shock with hypotension, electrolyte disturbances and acute renal failure. Cerebral oedema, coma, convulsions, and death are possible. (L741)
Expositionspfade	Inhalation (L741)oral (L741)dermal (L741)
Toxizitätsübersicht	The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes of the glycogenolysis and gluconeogenesis pathways. The mechanism of action of antimony remains unclear. However, some studies suggest that antimony combines with sulfhydryl groups including those in several enzymes important for tissue respiration. The antidotal action of BAL depends on its ability to prevent or break the union between antimony and vital enzymes. Moreover, the The cause of death is believed to be essentially the same as that in acute arsenic poisoning. (T18, L741, A238)
Signs and Symptoms	Abdominal pain, vomiting, diarrhea can result from inhalation of antimony. Dyspnea, headache, vomiting,cough, conjunctivitis, and bloody purulent discharge from nose can result from inhalation exposure. Skin or eye contact can cause pain and redness of the exposed surface. (T64, L741)

CAS No.

13059-67-1

Summenformel

C3H9Cl2Sb

Durchschnittliche Molmasse

237,77 g/mol

Monoisotopische Masse

235,91194 g/mol

SMILES

[CH3][Sb]([CH3])([CH3])([Cl])[Cl]

InChIKey

IEOZXTYTNPKDKQ-UHFFFAOYSA-L

PubChem CID

97653

EC No.

235-952-8

DTXSID

DTXSID80156630

Lokaler Name

Dichlorotrimethylantimon

Polarare Oberfläche (TPSA)

H-Brücken-Donoren

H-Brücken-Akzeptoren

Frei drehbare Bindungen

Schwere Atome

Formalladung

Komplexität

54,9

Schmelzpunkt

222-223 °C (dec.)(lit.)

Sicherheit & Vorschriften

Treatment

Following oral exposure to antimony, administer charcoal as a slurry (240 mL water/30 g charcoal). Following inhalation exposure, move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids. In case of eye exposure, irrigate exposed eyes with copious amounts of room temperature water for at least 15 minutes. Following dermal exposure, Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician may need to examine the area if irritation or pain persists. (T36)

Gesundheitliche Auswirkungen

Dermal exposure to antimony can cause antimony spots (papules and pustules around sweat and sebaceous glands). Antimony poisoning can also lead to pneumoconiosis. Alterations in pulmonary function and other effects including chronic bronchitis, chronic emphysema, inactive tuberculosis, pleural adhesions, and irritation can result from inhalation of antimony. Increased blood pressure can also result from antimony poisoning. Myocardial depression, vasodilation and fluid loss may cause shock with hypotension, electrolyte disturbances and acute renal failure. Cerebral oedema, coma, convulsions, and death are possible. (L741)

Expositionspfade

Inhalation (L741)oral (L741)dermal (L741)

Toxizitätsübersicht

The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes of the glycogenolysis and gluconeogenesis pathways. The mechanism of action of antimony remains unclear. However, some studies suggest that antimony combines with sulfhydryl groups including those in several enzymes important for tissue respiration. The antidotal action of BAL depends on its ability to prevent or break the union between antimony and vital enzymes. Moreover, the The cause of death is believed to be essentially the same as that in acute arsenic poisoning. (T18, L741, A238)

Signs and Symptoms

Abdominal pain, vomiting, diarrhea can result from inhalation of antimony. Dyspnea, headache, vomiting,cough, conjunctivitis, and bloody purulent discharge from nose can result from inhalation exposure. Skin or eye contact can cause pain and redness of the exposed surface. (T64, L741)

Carcinogen Classification