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N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan
FMOC-TRP-OH · FMOC-TRP · (((9H-fluoren-9-yl)methoxy)carbonyl)-L-tryptophan · FMOC-L-TRP-OH · FMOC-L-TRP · (S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(1H-indol-3-yl)propanoic acid · FMOC-TRYPTOPHAN · FMOC-L-TRYPTOPHAN
![Molekülstruktur von N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan](/img/chemical/978343.png)
Identifikatoren & physikalische Daten
| CAS No. | 35737-15-6 |
|---|---|
| Summenformel | C26H22N2O4 |
| Durchschnittliche Molmasse | 426,5 g/mol |
| SMILES | O=C(N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)OCC1c2ccccc2-c2ccccc21 |
| InChIKey | MGHMWKZOLAAOTD-DEOSSOPVSA-N |
| PubChem CID | 978343 |
| ChEMBL | CHEMBL292051 |
| DTXSID | DTXSID30875541 |
| Lokaler Name | N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan |
Chemische & physikalische Eigenschaften
| XLogP | 4,1 |
|---|---|
| Polarare Oberfläche (TPSA) | 91,4 |
| H-Brücken-Donoren | 3 |
| H-Brücken-Akzeptoren | 4 |
| Frei drehbare Bindungen | 7 |
| Schwere Atome | 32 |
| Formalladung | 0 |
| Komplexität | 663 |
| Schmelzpunkt | 182-185 °C(lit.) |
| Siedepunkt | 541.92°C (rough estimate) |
| Dichte | 1.2501 (rough estimate) |
| Brechungsindex | -28.5 ° (C=1, DMF) |
| Lagerbedingungen | 2-8°C |
| Löslichkeit | almost transparency in Pyridine |
| Aggregatzustand | powder to crystal |
| pKa (Säurekonstante) | 3.89±0.10(Predicted) |
| Farbe | White to Almost white |
| BRN | 4216624 |
| Hauptanwendungen | peptide synthesis |
| InChIKey | MGHMWKZOLAAOTD-DEOSSOPVSA-N |
| SMILES | C(O)(=O)[C@H](CC1C2=C(C=CC=C2)NC=1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O |
| CAS Datenbank | 35737-15-6(CAS DataBase Reference) |
Sicherheit & Vorschriften
| Wassergefährdungsklasse (WGK) | 3 |
|---|---|
| Zollcode | 2933 99 80 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 22-24/25-36/37/39-27-26 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
Nα-Fmoc-L-tryptophan is an N-Fmoc protected form of L-Tryptophan (T947210). L-Tryptophan is an essential amino acid that is important for cell proliferation and the biosynthesis of proteins. It is a precursor to Serotonin (HCl: S274980), a neurotransmitter that compound that aids in sleep and mental state. L-Tryptophan is also thought to cause eosinophilia-myalgia syndrome.