Clopidogrel Hydrochloride
Grundinformationen
- CAS
120202-65-5- Standard-SMILES
COC(=O)[C@H](c1ccccc1Cl)N1CCc2sccc2C1.Cl- InChIKey
XIHVAFJSGWDBGA-RSAXXLAASA-N- Summenformel
- C16H17Cl2NO2S
- Durchschnittliche Molmasse
- 358,3 g/mol
- Monoisotopische Masse
- 357,0357053
Überblick
Clopidogrel Hydrochloride is the hydrochloride salt form of clopidogrel, a thienopyridine, with antiplatelet activity. Clopidogrel targets, irreversibly binds to and alters the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor, inhibiting ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, and inhibiting fibrinogen binding to platelets and platelet adhesion and aggregation. This results in increased bleeding time.
Namen und Bezeichner
- Bevorzugter Name
- Clopidogrel Hydrochloride
- IUPAC
- methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate;hydrochloride
- Englischer Name
- (S)-methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate hydrochloride
- Summenformel
- C16H17Cl2NO2S
- Molmasse
- 358.28
Namen und Synonyme
Clopidogrel hydrochloride120202-65-5clopidogrel HCl426O7XWS6YCLOPIDOGREL-HCSCLOPIDOGREL-TADCLOPIDOGREL-DURACLOPIDOGREL-KRKACLOPIDOGREL MYLANCLOPIDOGREL QUALIMEDCLOPIDOGREL TEVA PHARMADTXSID40152734
Weitere Namen anzeigen
D3-Clopidogrel hydrochlorideClopidogrel D3 hydrochlorideMethyl(2S)-2-(2-chlorophenyl)-2-[6,7-dihydrothieno[3,2-c]pyridin-5(4h)-yl]acetatehydrochloride(S)-methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate hydrochloridemethyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate,hydrochlorideClopidogrel D3 hydrochlorideQ: What is Clopidogrel D3 hydrochloride Q: What is the CAS Number of Clopidogrel D3 hydrochloride Q: What is the storage condition of Clopidogrel D3 hydrochloride Q: What are the applications of Clopidogrel D3 hydrochloride
CLOPIDOGREL TEVA GENERICS B.V.RefChem:127082DTXCID6075225THIENO(3,2-C)PYRIDINE-5(4H)-ACETIC ACID, ALPHA-(2-CHLOROPHENYL)-6,7-DIHYDRO-, METHYL ESTER, HYDROCHLORIDE, (S)-UNII-426O7XWS6Ymethyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate;hydrochlorideThieno[3,2-c]pyridine-5(4H)-acetic acid, alpha-(2-chlorophenyl)-6,7-dihydro-, methyl ester, hydrochloride (1:1), (alphaS)-clopidogrel-hydrochlorid
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 57,8 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 4
- Frei drehbare Bindungen
- 4
- Schwere Atome
- 22
- Formalladung
- 0
- Komplexität
- 381
Experimentelle und physikochemische Eigenschaften
Human DrugsEMA approved medicines: Human medicine
Physikochemische Eigenschaften
- storage temp.
- 2 · 2-8°C
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P260, P261, P264, P264+P265, P270, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P308+P316, P319, P321, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Gefahrenhinweise
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Sicherheitsdaten
- wgk
- WGK 3
- Speicherklasse
- 11 - Combustible Solids
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
Compounds that bind to and block the stimulation of PURINERGIC P2Y RECEPTORS. Included under this heading are antagonists for specific P2Y receptor subtypes.
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