HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(1-Methyl-3-piperidyl)methanol
(1-Methylpiperidin-3-yl)methanol · 1-Methy-3-piperidinemethanol · 1-METHYLPIPERIDINE-3-METHANOL · 1-METHYL-3-PIPERIDINEMETHANOL · N-Methylpiperidine-3-methanol · N-METHYLPIPERIDINE-3-CARBINOL · N-Methyl-3-piperidinecarbinol · N-METHYL-3-PIPERIDINE METHANOL
Identifikatoren & physikalische Daten
| CAS No. | 7583-53-1 |
|---|---|
| Summenformel | C7H15NO |
| Durchschnittliche Molmasse | 129,2 g/mol |
| Monoisotopische Masse | 129,1153641 g/mol |
| SMILES | CN1CCCC(CO)C1 |
| InChIKey | UGXQXVDTGJCQHR-UHFFFAOYSA-N |
| PubChem CID | 97998 |
| EC No. | 231-488-5 |
| DTXSID | DTXSID80871194 |
| Lokaler Name | (1-Methyl-3-piperidyl)methanol |
Chemische & physikalische Eigenschaften
| XLogP | 0,3 |
|---|---|
| Polarare Oberfläche (TPSA) | 23,5 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 9 |
| Formalladung | 0 |
| Komplexität | 85 |
| Siedepunkt | 140-145 °C |
| Dichte | 1.01 |
| Brechungsindex | 1.4772-1.4792 |
| Flammpunkt | 94 °C |
| Lagerbedingungen | Sealed in dry,Room Temperature |
| Aggregatzustand | clear liquid |
| pKa (Säurekonstante) | 14.93±0.10(Predicted) |
| Farbe | Colorless to Yellow to Orange |
| BRN | 103713 |
| CAS Datenbank | 7583-53-1(CAS DataBase Reference) |
| NIST chemische Informationen | 1-Methyl-3-piperidinemethanol(7583-53-1) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 6 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | 3-Piperidinemethanol, 1-methyl-: Does not have an individual approval but may be used under an appropriate group standard |
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Zollcode | 29333990 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 24/25-45-36/37/38-23 |
| Gefahrenklasse | IRRITANT |
| Verpackungsgruppe | III |
Anwendungen & Verwendung
Verwenden
Hydroxymethyl-N-methylpiperidine is used in the preparation of pyrimidines as FGFR3 tyrosine kinase inhibitors as well as for potent pyrazine c-Src inhibitors in the treatment of ischemic stroke.