U 83836E
Grundinformationen
- CAS
137018-55-4- Standard-SMILES
Cc1c(C)c2c(c(C)c1O)CC[C@](C)(CN1CCN(c3cc(N4CCCC4)nc(N4CCCC4)n3)CC1)O2.Cl.Cl- InChIKey
KJGXSMZHYBXPIS-ZHXNKHNVSA-N- Summenformel
- C30H46Cl2N6O2
- Durchschnittliche Molmasse
- 593,6 g/mol
- Monoisotopische Masse
- 592,3059301
Namen und Bezeichner
- Bevorzugter Name
- U 83836E
- IUPAC
- (2R)-2-[[4-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)piperazin-1-yl]methyl]-2,5,7,8-tetramethyl-3,4-dihydrochromen-6-ol;dihydrochloride
- Englischer Name
- U-83836E
- Summenformel
- C30H45ClN6O2
- Molmasse
- 557.18
Namen und Synonyme
137018-55-4u-83836eU 83836ERefChem:933716U83836EU 82836E(2R)-2-[[4-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)piperazin-1-yl]methyl]-2,5,7,8-tetramethyl-3,4-dihydrochromen-6-ol;dihydrochloride(2R)-2-[[4-(2,6-Di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]methyl]-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-6-ol dihydrochlorideorb1703960CHEMBL3216717SCHEMBL29435423DTXSID801371791
Weitere Namen anzeigen
PNU-83836EU83836E,U 83836E(-)-2-((4-(2,6-DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)METHYL)-3,4-DIHYDRO-2,3,7,8-TETRAMETHYL-2H-1-BENZOPYRAN-6-OL, 2HCL(-)-2-((4-(2,6-DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)METHYL)-3,4-DIHYDRO-2,3,7,8-TETRAMETHYL-2H-1-BENZOPYRAN-6-OL, 2HCL
PNU 83836EAKOS040745407CID 9808654MS-33213ST110547U 83836 dihydrochloride; PNU 83836EHY-117762CS-0067727
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 68,2 Ų
- H-Brücken-Donoren
- 3
- H-Brücken-Akzeptoren
- 8
- Frei drehbare Bindungen
- 5
- Schwere Atome
- 40
- Formalladung
- 0
- Komplexität
- 783
Physikochemische Eigenschaften
- storage temp.
- -20 °C · Desiccate at -20°C
- Löslichkeit
- Soluble in DMSO
- Aggregatzustand
- Solid
- Farbe
- Light yellow to yellow
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues.
Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
Drugs that are used to treat asthma.
Anwendungen
VerwendenU 82836E is an iron-dependent lipid peroxidation inhibitor. This free radical scavenger has potent neuroprotective effects against ischemic injury and diabetic neuropathy.
Anbieter10 Anbieter
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MedBio脉铂医药021-69568360 18916172912 · [email protected]
杭州杰恒化工有限公司0571-87396432 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
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