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Dipropylene glycol methyl ether acetate

HCID 9815489
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GrundinformationenNamen und BezeichnerEigenschaftenSicherheit und RegulatorischesChemie und IndustrieZugehörige ReaktionenNotizen zur Verbindung
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Grundinformationen

CAS
212484-39-4
Standard-SMILES
COCC(C)OCC(C)OC(C)=O
InChIKey
LAVARTIQQDZFNT-UHFFFAOYSA-N
Summenformel
C9H18O4
Durchschnittliche Molmasse
190,24 g/mol
Monoisotopische Masse
190,12050905

Namen und Bezeichner

Bevorzugter Name
Dipropylene glycol methyl ether acetate
IUPAC
1-(1-methoxypropan-2-yloxy)propan-2-yl acetate
Englischer Name
Di(propylene glycol) methyl ether acetate
Summenformel
C9H18O4
Molmasse
190.24

Namen und Synonyme

88917-22-0PPG-2 methyl ether acetatedipropylene glycol methyl ether acetateDowanol DPMA5455FZE9RBPropanol, 1(or 2)-(2-methoxymethylethoxy)-, acetateRefChem:1083816406-880-6618-219-0Dipropyleneglycol methyl ether acetate1-(1-methoxypropan-2-yloxy)propan-2-yl AcetateNIOSH/UB7875850
Weitere Namen anzeigen
DPMAdipropyleneglycolmonomethyletheracetatePD-125944Arcosolv DPMADOWANOL(R) DPMADOWANOL(TM) DPMAARCOSOLV(R) DPMADi methyl ether acetate
UB787585001-((1-Methoxypropan-2-yl)oxy)propan-2-yl acetate1-[(1-Methoxypropan-2-yl)oxy]propan-2-yl acetate1-(2-Methoxy-1-methylethoxy)-2-propanol acetate (ester)2-Propanol, 1-(2-methoxy-1-methylethoxy)-, acetate (ester)UNII-5455FZE9RBSCHEMBL145638CHEMBL1255792

Datenbank-Bezeichner

CAS
212484-39-4、88917-22-0
PubChem CID
9815489
DTXSID

Eigenschaften

Berechnete Struktureigenschaften

XLogP
0,7
Polarare Oberfläche (TPSA)
44,8 Ų
H-Brücken-Donoren
0
H-Brücken-Akzeptoren
4
Frei drehbare Bindungen
7
Schwere Atome
13
Formalladung
0
Komplexität
147

Experimentelle und physikochemische Eigenschaften

SolventsSolvents -> Glycol Ethers (P Series)
CosmeticsCosmetic ingredients (PPG-2 Methyl Ether Acetate) -> CIR (Cosmetic Ingredient Review)
FragrancesFragrance Ingredient (Propanol, 1(or 2)-(2-methoxymethylethoxy)-, acetate) -> IFRA transparency List
LogP · 2 Einträge

0.803

0.8

Density · 2 Einträge

0.98 g/cm³

Relative density of the vapour/air-mixture at 20 °C (air = 1): 1.00

Viscosity1.7 mm²/s at 25 °C
SolubilitySolubility in water, g/100ml: 16 (good)
Flash Point86 °C
Boiling Point209 °C
Melting Point-25.5 °C

Sicherheit und Regulatorisches

Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 17.9% (78 of 435) of reports.

Warning

H302 (40.7%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 435 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

This chemical does not meet GHS hazard criteria for 32.5% (119 of 366) of reports.

Gefahrenhinweise

Regulatory Information · 5 Einträge

Chemical: Propanol, 1(or 2)-(2-methoxymethylethoxy)-, acetate

Propanol, 1(or 2)-(2-methoxymethylethoxy)-, acetate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Propanol, 1(or 2)-(2-methoxymethylethoxy)-, acetate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

REACH registered substance: A mixture of RR and RS isomers of: (2-(2-methoxy-1-methyl)ethoxy)-1-methylethyl acetate; (2-(2-methoxy-2-methyl)ethoxy)-1-methylethyl acetate; (2-(2-methoxy-2-methyl)ethoxy)-2-methylethyl acetate; (2-(2-methoxy-1-methyl)ethoxy)-2-methylethyl acetate (EC: 406-880-6)

Propanol, 1(or 2)-(2-methoxymethylethoxy)-, acetate: Does not have an individual approval but may be used under an appropriate group standard

Fire HazardsCombustible. Above 86 °C explosive vapour/air mixtures may be formed.
Hazards Summary · 1 Eintrag

Commercial product is a mixture of up to 4 isomers due to the position of the internal ether being linked to either the primary or secondary carbon atoms; Category members demonstrate LOAELs of 1,000 mg/kg/day (highest tested dose) in 13-week oral studies of rats for increased liver and kidney weight without corresponding histopathology; No hematotoxicity observed; Eye and nasal mucosa irritation and increased liver weights, some with corresponding histopathology, in 2-week inhalation studies of rats; [OECD SIDS: Propylene Glycol Ethers - 2003]

Chemie und Industrie

Verwendung und Herstellung

Uses · 3 Einträge

CIR ingredient: PPG-2 Methyl Ether Acetate

Used as an active and tailing solvent in coatings and a solvent in silkscreen printing inks; [OECD SIDS: Propylene Glycol Ethers - 2003]

Painting (Solvents) [Category: Paint]

U.S. Production2023: 10,000,000 - <25,000,000 lb
Consumer UsesFragrance
Industry UsesNot Known or Reasonably Ascertainable
Household ProductsInformation on 26 consumer products that contain PPG-2 Methyl Ether Acetate
 in the following categories is provided:
Use Classification · 3 Einträge

EPA Safer Chemical Functional Use Classes -> Solvents

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Fragrance Ingredients

General Manufacturing Information · 2 Einträge

Printing Ink Manufacturing

Propanol, 1(or 2)-(2-methoxymethylethoxy)-, acetate: ACTIVE

Anwendungen

VerwendenDi(propylene glycol) methyl ether acetate is a solvent, it is also used as a formula stabilizer and to improve skin penetration in topically applied acne preparations containing erythromycin.

Anbieter100 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]

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Auf dieser SeiteGrundinformationenNamen und BezeichnerEigenschaftenSicherheit und RegulatorischesChemie und IndustrieZugehörige ReaktionenNotizen zur Verbindung
DTXSID40858784
ChEMBL
CHEMBL1255792
UNII
5455FZE9RB
EC Number
406-880-6、618-219-0
Nikkaji
J1.013.198G
Vapor Density
Relative vapor density (air = 1): 6.56
Vapor Pressure · 2 Einträge

0.12 [mmHg]

Vapor pressure, Pa at 25 °C: 17

Physikochemische Eigenschaften

Siedepunkt
200 °C · 200 °C(lit.)
Dichte
0.97 g/mL · 0.97 g/mL at 25 °C(lit.)
Dampfdruck
10.4 Pa · 10.4Pa at 20℃
Brechungsindex
20 · n20/D 1.417(lit.)
Flammpunkt
186 °F · 186 °F
Löslichkeit
750 g/L · 750g/L in organic solvents at 20 ℃
Aggregatzustand
liquid
Wasserlöslichkeit
183 g/L · 183g/L at 20℃
Kosmetik-Inhaltsstoffe Funktionen
SOLVENT
InChI
InChI=1S/C9H18O4/c1-7(5-11-4)12-6-8(2)13-9(3)10/h7-8H,5-6H2,1-4H3
InChIKey
LAVARTIQQDZFNT-UHFFFAOYSA-N
SMILES
C(C(C)OC(=O)C)OC(C)COC
LogP
0.61 at · 0.61 at 20℃
CAS Datenbank
88917 · 88917-22-0(CAS DataBase Reference)
EPA chemische Informationen
1 · Propanol, 1(or 2)-(2-methoxymethylethoxy)-, acetate (88917-22-0)
EPA Safer ChemicalChemical: Propanol 1 (or 2)-2-methoxymethyl ethoxy, acetate
Chemical DangersReacts with strong acids and strong oxidants.
Hazard Classes and Categories · 3 Einträge

Acute Tox. 4 (49.2%)

Acute Tox. 4 (40.7%)

Flammable liquids - Category 4

Explosive Limits and PotentialExplosive limits , vol% in air: 1.21-5.35

Sicherheit und Schutzausrüstung

Fire FightingUse water spray, dry powder, alcohol-resistant foam, carbon dioxide.
First Aid Measures · 3 Einträge

Fresh air, rest.

Rinse skin with plenty of water or shower.

Rinse mouth. Do NOT induce vomiting.

Safe StorageSeparated from strong acids and strong oxidants.
Spillage DisposalPersonal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking liquid in sealable containers. Wash away spilled liquid with plenty of water.
Eye PreventionWear safety goggles.
Fire PreventionNO open flames. Above 86 °C use a closed system and ventilation.
Inhalation RiskNo indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.
Skin PreventionProtective gloves.
Ingestion PreventionDo not eat, drink, or smoke during work.
Inhalation PreventionUse ventilation.
Effects of Short Term ExposureIf swallowed the substance may cause vomiting and could result in aspiration pneumonitis.

Toxikologische Informationen

Adverse EffectsNeurotoxin - Acute solvent syndrome
Toxicity SummarySafe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org
Toxicity DataLC50 (rat) > 5,700 mg/m3

Sicherheitsdaten

wgk
3
tsca
TSCA listed
ridadr
NA 1993 / PGIII
hs_code
29153900
risk_code
36/37/38
hazard_code
Xi
safety_code
26-36
Speicherklasse
10 - Combustible liquids
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