HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(±)-4-Fluorphenylglycin
2-amino-2-(4-fluorophenyl)acetic acid · 4-FLUORO-DL-ALPHA-PHENYLGLYCINE · DL-4-Fluorine · DL-PHg(4-F)-OH · h-dl-phg(4-f)-oh · RARECHEM AK ML 0519 · 4-FLUOROPHENYLGLYCINE · DL-4-Flurophenylglycine
Identifikatoren & physikalische Daten
| CAS No. | 7292-73-1 |
|---|---|
| Summenformel | C8H8FNO2 |
| Durchschnittliche Molmasse | 169,15 g/mol |
| Monoisotopische Masse | 169,05390666 g/mol |
| SMILES | NC(C(=O)O)c1ccc(F)cc1 |
| InChIKey | JKFYKCYQEWQPTM-UHFFFAOYSA-N |
| PubChem CID | 98313 |
| EC No. | 230-724-4 |
| DTXSID | DTXSID801373109 |
| Lokaler Name | (±)-4-Fluorphenylglycin |
Chemische & physikalische Eigenschaften
| XLogP | -1,6 |
|---|---|
| Polarare Oberfläche (TPSA) | 63,3 |
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 4 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 12 |
| Formalladung | 0 |
| Komplexität | 166 |
| Schmelzpunkt | ≥300 °C(lit.) |
| Siedepunkt | 289.9±30.0 °C(Predicted) |
| Dichte | 1.347±0.06 g/cm3(Predicted) |
| Lagerbedingungen | Keep in dark place,Inert atmosphere,Room temperature |
| pKa (Säurekonstante) | 1.90±0.10(Predicted) |
| Aggregatzustand | Powder |
| Farbe | Pale yellow |
| BRN | 2804849 |
| InChI | InChI=1S/C8H8FNO2/c9-6-3-1-5(2-4-6)7(10)8(11)12/h1-4,7H,10H2,(H,11,12) |
| InChIKey | JKFYKCYQEWQPTM-UHFFFAOYSA-N |
| SMILES | C(C1C=CC(F)=CC=1)(N)C(=O)O |
| CAS Datenbank | 7292-73-1(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (100%)Eye Irrit. 2A (100%)STOT SE 3 (100%) |
| Wassergefährdungsklasse (WGK) | 3 |
| Zollcode | 29224999 |
| R-Sätze (R) | 36/37/38-22 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 22-24/25 |
| Gefahrenklasse | IRRITANT |
Anwendungen & Verwendung
Verwenden
L-4-Fluorophenylglycine (L-4FPG), an inhibitor of the neutral amino acid transporter ASCT1/2, has been shown to regulate extracellular D-serine levels.