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Ferrous glycinate

HCID 9837124
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Grundinformationen

CAS
20150-34-9
Standard-SMILES
NCC(=O)[O-].NCC(=O)[O-].[Fe+2]
InChIKey
GIPOFCXYHMWROH-UHFFFAOYSA-L
Summenformel
C4H8FeN2O4
Durchschnittliche Molmasse
203,96 g/mol
Monoisotopische Masse
203,983342

Überblick

Ferrous bisglycinate is a chelate that is used as a source of dietary iron. Forming a ring structure when reacting with glycine, ferrous bisglycinate acts as both a chelate and a nutritionally functional. It is found in foods for food enrichment or in supplements for the treatment of iron deficiency or iron deficiency anemia.

Namen und Bezeichner

Bevorzugter Name
Ferrous glycinate
IUPAC
bis(2-aminoacetate);iron(2+)
Englischer Name
Ferrous Bisglycinate
Summenformel
C4H8FeN2O4
Molmasse
203.96

Namen und Synonyme

Ferrous bisglycinate20150-34-9FERROUS GLYCINATEIron Bis-glycinateBisglycino-iron(II) chelateIron bis-glycinate chelateDTXSID30173978SFW1D987QVRefChem:140305DTXCID2096469Bis(glycinato-kappaN,kappaO)ironiron trisglycinate
Weitere Namen anzeigen
FERROCHELFerric GlycineFerrous GglycinateFerrous Bis-glycineIron(II) bisglycinateFERROUS(II) GLYCINATEFerric Glycine CoMplexBisglycine iron(II) salt
2-aminoacetate;iron(2+)MFCD07780318FERROUSBISGLYCINATEC4H8FeN2O4Iron(II) glycinateferrous;2-aminoacetateBis(2-aminoacetoxy)ironIron(2+) bis(aminoacetate)

Datenbank-Bezeichner

CAS
20150-34-9
PubChem CID
9837124
DTXSID
DTXSID30173978
ChEMBL
CHEMBL4297753
UNII

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
132 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
6
Frei drehbare Bindungen
0
Schwere Atome
11
Formalladung
0
Komplexität
37,4

Physikochemische Eigenschaften

Schmelzpunkt
162 °C · >162°C (dec.)
Siedepunkt
150 ℃ · 150℃ at 101kPa
Dichte
1.898 at · 1.898 at 20℃
Dampfdruck
0 · 0-0Pa at 20-25℃
storage temp.
Keep in dark place,Inert atmosphere,Room temperature
Löslichkeit
Aqueous Acid (Slightly)
Aggregatzustand
Solid
Farbe
Pale Brown to Brown
Wasserlöslichkeit
35.71 mg/mL · Water: 35.71 mg/mL (176.83 mM)
Stabilität
Hygroscopic
Kosmetik-Inhaltsstoffe Funktionen
SKIN CONDITIONINGANTIOXIDANT
InChI
InChI=1S/2C2H4NO2.Fe/c2*3-1-2(4)5;/h2*3H,1H2,(H,4,5);/q2*-1;+4/p-2
InChIKey
MECJLZIFMOMXPW-UHFFFAOYSA-L
SMILES
O=C1CN[Fe+2]2(NCC(=O)[O-]2)[O-]1
LogP
-3.47 at · -3.47 at 20℃ and pH7

Sicherheit und Regulatorisches

Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.

GHS-Klassifizierung

GHS Classification · 5 Einträge

This chemical does not meet GHS hazard criteria for 2.5% (4 of 162) of reports.

Warning

H302 (32.7%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P321, P330, P332+P317, P337+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 162 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory Information · 3 Einträge

Regulation (EC) No 178/2002 (amended)

REACH registered substance: Iron, bis(glycinato-.kappa.N,.kappa.O)- (EC: 606-444-7)

Ferrous bisglycinate: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazard Classes and CategoriesAcute Tox. 4 (32.7%)

Sicherheitsdaten

Toxizität
LD50 orally in rats: 560 mg iron/kg (Jeppsen)

Chemie und Industrie

Verwendung und Herstellung

Use ClassificationFood Additives -> NUTRIENT_SUPPLEMENT -> JECFA Functional Classes
Anwendungen · 2 Einträge

BeschreibungFerrous Bisglycinate, also known as ferrous glycinate, is an iron (II) chelate with an iron to glycine ratio of 1:2. It has an octahedral structure with two water molecules and two chelated glycinate ions coordinated to the central ferrous iron. Ferrous glycinate (processed with citric acid) also contains citric acid. It is manufactured by reaction of reduced iron with glycine in the presence of citric acid. The resulting product is spray dried without prior removal of the citric acid. The substance is highly hygroscopic and may contain water in variable amounts.

VerwendenFerrous Bisglycinate is an iron-amio acid chelate. In this the iron is protected from the action of absorption inhibitors by being bound to the amino acid and glycine. Ferrous bisglycinate is the major amino acid chelate produced commercially, although ferrous trisglycinate and ferric glycinate are also available. A patented ferrous bisglycinate compound, manufactured by Albion Laboratories, Utah, USA, has been used in most published studies. The chelate is reported to be formed by two glycine molecules combining with ferrous iron in a double heterocyclic ring structure. Evidence would suggest that iron is protected from inhibitors by the structure, since iron absorption is one to 3.5 times higher than from ferrous sulfate when added to bread rolls and milk products containing inhibitors such as phytate and calcium. Ferrous bisglycinate is more bioavailable than ferrous trisglycinate.

Anbieter108 Anbieter

Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]
山东天微医药科技有限公司+86-18653895227 · [email protected]
上海康朗生物科技有限公司

Zugehörige Reaktionen

2
Reaktionsaufzeichnung erstellen
Reaktionsgleichung von HRID 387489
HRID 387489als Produktuspto-grants-2013_02
Reaktionsgleichung von HRID 504074
HRID 504074als Eduktuspto-grants-2010_08

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SFW1D987QV
EC Number
606-444-7
Nikkaji
J898.250C
Oberflächenspannung
72.87 mN/m · 72.87mN/m at 1g/L and 20℃
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