HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Natrium-(-)-2-(6-methoxy-2-naphthyl)propionat
aleve · Naprelan · Anax · (S)-6-METHOXY-ALPHA-METHYL-2-NAPHTHALENEACETIC ACID SODIUM SALT · Anaprox · aproxen sodium · NAPROXENSODIUM,USP · NAPROXEN SODIUM SALT
Identifikatoren & physikalische Daten
| CAS No. | 26159-34-2 |
|---|---|
| Summenformel | C14H14NaO3 |
| Durchschnittliche Molmasse | 253,25 g/mol |
| Monoisotopische Masse | 253,08406359 g/mol |
| SMILES | COc1ccc2cc([C@H](C)C(=O)O)ccc2c1.[Na] |
| InChIKey | CNQOEXOJUIMDHW-FVGYRXGTSA-N |
| PubChem CID | 9837916 |
| Lokaler Name | Natrium-(-)-2-(6-methoxy-2-naphthyl)propionat |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 46,5 |
|---|---|
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 3 |
| Frei drehbare Bindungen | 3 |
| Schwere Atome | 18 |
| Formalladung | 0 |
| Komplexität | 277 |
| Schmelzpunkt | 250-251°C |
| Dichte | 1.2 g/cm³ |
| Lagerbedingungen | Inert atmosphere,Room Temperature |
| Löslichkeit | Freely soluble in water, freely soluble or soluble in methanol, sparingly soluble in ethanol (96 per cent).Soluble in water up to 100mg/mlSoluble in methanol and chloroform. Slightly soluble in ether. Insoluble in water. |
| Aggregatzustand | Solid |
| Farbe | White to Off-White |
| Biologische Quelle | synthetic (organic) |
| Hauptanwendungen | pharmaceutical (small molecule) |
| InChI | InChI=1/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/q+1/p-1/t9-/s3 |
| InChIKey | CDBRNDSHEYLDJV-OVMXBOEKNA-M |
| SMILES | C12C=CC(OC)=CC1=CC=C([C@H](C)C([O-])=O)C=2.[Na+] |&1:11,r| |
| CAS Datenbank | 26159-34-2(CAS DataBase Reference) |
Sicherheit & Vorschriften
| Wassergefährdungsklasse (WGK) | 3 |
|---|---|
| UN-Transportnummer | 3249 |
| Zollcode | 2918992090 |
| RTECS-Nr. | QJ1047000 |
| R-Sätze (R) | 22-61 |
| Gefahrensymbole | Xn,T |
| Sicherheitshinweise (S) | 53-45 |
| Gefahrenklasse | 6.1(b)Acute Tox. 4 OralRepr. 1A |
| Verpackungsgruppe | III |
| Lagerklasse | 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects |
Anwendungen & Verwendung
Verwenden
A cyclooxygenase inhibitorNaproxen sodium acts as a nonselective inhibitor of Cox-1 and Cox-2. It serves as an anti-inflammatory agent with analgesic and antipyretic properties. Further, it is used in the treatment of rheumatoid arthritis and other rheumatic or musculoskeletal disorders, dysmenorrhea and acute gout.