methyl (5S,6R,7E,9E,11Z,13E,15R)-5,6,15-trihydroxyicosa-7,9,11,13-tetraenoate
Grundinformationen
- CAS
97643-35-1- Standard-SMILES
CCCCC[C@@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCC(=O)OC- InChIKey
UBPCKDCSZPRQJP-LUOMNJIASA-N- Summenformel
- C21H34O5
- Durchschnittliche Molmasse
- 366,5 g/mol
- Monoisotopische Masse
- 366,24062418
Namen und Bezeichner
- Bevorzugter Name
- methyl (5S,6R,7E,9E,11Z,13E,15R)-5,6,15-trihydroxyicosa-7,9,11,13-tetraenoate
- IUPAC
- methyl (5S,6R,7E,9E,11Z,13E,15R)-5,6,15-trihydroxyicosa-7,9,11,13-tetraenoate
- Englischer Name
- 5(S),6(R),15(S)-Trihete methyl ester
- Summenformel
- C21H34O5
- Molmasse
- 366.49
Namen und Synonyme
SCHEMBL23347498DTXSID70135775697643-35-1lipoxin A methyl esterLipoxin A4 Methyl Ester Solution5(S),6(R)-LIPOXIN A4 METHYL ESTER5(S),6(R),15(S)-Trihete methyl ester5S,6R,15S-TRIHYDROXY-7E,9E,11Z,13E-EICOSATETRAENOIC ACID, METHYL ESTER7,9,11,13-Eicosatetraenoic acid, 5,6,15-trihydroxy-, methyl ester, (5S,6R,7E,9E,11Z,13E,15S)-
Datenbank-Bezeichner
- CAS
97643-35-1- PubChem CID
- 9842121
- DTXSID
DTXSID701357756- Nikkaji
- J2.446.227G
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 3,4
- Polarare Oberfläche (TPSA)
- 87 Ų
- H-Brücken-Donoren
- 3
- H-Brücken-Akzeptoren
- 5
- Frei drehbare Bindungen
- 15
- Schwere Atome
- 26
- Formalladung
- 0
- Komplexität
- 465
Physikochemische Eigenschaften
- Siedepunkt
- 540.2 · 540.2±50.0 °C(Predicted)
- Dichte
- 1.056 · 1.056±0.06 g/cm3(Predicted)
- Flammpunkt
- 10 ℃ · 10℃ (tag closed test)
- storage temp.
- -80 °C · Store at -80°C
- Löslichkeit
- 50 mg/ml; · DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml
- pka
- 13.38 · 13.38±0.20(Predicted)
Chemie und Industrie
Anwendungen
BeschreibungLipoxin A4 methyl ester (LXA4 methyl ester) is a more lipid soluble, prodrug formulation of the transcellular metabolite LXA4. LXA4 is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of 15-HETE or 15-HpETE with human leukocytes. LXA4 is equipotent to leukotriene B4 (LTB4) in inducing superoxide generation in human neutrophils at 0.1 μM. LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural killer cell inhibition, and monocyte migration and adhesion.
Anbieter4 Anbieter
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
ChemeGen 中国18818260767 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
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