Cyazofamid

Cyazofamide · RANMAN · MILDICUT · CYAZOFAMID STANDARD · 4-chloro-2-cyano-N,N-diMethyl-5-(p-tolyl)-1H-iMidazole-1-sulfonaMide · 4-Chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide · DOCIOUS · IKF-916

https://huagongshe.com/de/chemical/9862076

Identifikatoren & physikalische Daten

CAS No.	120116-88-3
Summenformel	C13H13ClN4O2S
Durchschnittliche Molmasse	324,79 g/mol
Monoisotopische Masse	324,04477434 g/mol
SMILES	Cc1ccc(-c2c(Cl)nc(C#N)n2S(=O)(=O)N(C)C)cc1
InChIKey	YXKMMRDKEKCERS-UHFFFAOYSA-N
PubChem CID	9862076
ChEMBL	CHEMBL1863429
ChEBI	CHEBI:81841
EC No.	601-671-8
DTXSID	DTXSID9034492

Chemische & physikalische Eigenschaften

XLogP	2,6
Polarare Oberfläche (TPSA)	87,4
H-Brücken-Donoren	0
H-Brücken-Akzeptoren	5
Frei drehbare Bindungen	3
Schwere Atome	21
Formalladung	0
Komplexität	516
pH	pH = 4.9 at 25 °C
Pestizide	Agrochemicals -> Pesticide active substancesActive substance -> EU Pesticides database: ApprovedPesticides -> FungicidesEnvironmental transformation -> Pesticides (parent, predecessor)Pesticide (Cyazofamid) -> USDA PDB
LogP (Verteilungskoeffizient)	log Kow = 3.2
Geruch	Odorless
Dichte	1.446 at 20 °C1.38±0.1 g/cm3(Predicted)
Color/Form	Ivory powder
Löslichkeit	Solvent solubility (all in g/100 mL, 21.2 °C): hexane, 0.003methanol, 0.174, acetonitrile, 3.095, dichloroethane, 10.212toluene, 0.600, ethyl acetate, 1.649acetone, 4.564, octanol, 0.004In water, 0.107 at pH 70.121 at pH 50.109 at pH 9 (all in mg/L at 20 °C)DMF: 15 mg/mlDMSO: 10 mg/ml
Endocrine Disruptors	Potential endocrine disrupting compound
Schmelzpunkt	152.7 °C152.7°
Dampfdruck	1.3X10-2 mPa /9.75X10-8 mm Hg/ at 35 °C
Physical Description	Ivory odorless solid[Merck Index]
Dissociation Constants	No pKa evident in pH range 2-12
Siedepunkt	498.2±37.0 °C(Predicted)
Flammpunkt	4 °C
Lagerbedingungen	-20°C
pKa (Säurekonstante)	-6.61±0.70(Predicted)
Aggregatzustand	Solid
Farbe	White to off-white
Henry-Konstante	2.5×101 mol/(m3Pa) at 25℃, HSDB (2015)
Hauptanwendungen	agricultureenvironmental
InChI	InChI=1S/C13H13ClN4O2S/c1-9-4-6-10(7-5-9)12-13(14)16-11(8-15)18(12)21(19,20)17(2)3/h4-7H,1-3H3
InChIKey	YXKMMRDKEKCERS-UHFFFAOYSA-N
SMILES	C1(C#N)N(S(N(C)C)(=O)=O)C(C2=CC=C(C)C=C2)=C(Cl)N=1
LogP (Verteilungskoeffizient)	1.750 (est)
EPA chemische Informationen	Cyazofamid (120116-88-3)

Sicherheit & Vorschriften

GHS-Einstufung	WarningH400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]P273, P391, and P501 (click each P-code to see the statement)H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
Regulatorische Informationen	Commission Regulation No 844/2012Cyazofamid is listed in the dataset of EPA Human Health Benchmarks for Pesticides under the Safe Drinking Water Act (40 eCFR 141)03/23/EC, Reg. (EU) 2016/950, Reg. (EU) 2017/841, Reg. (EU) 2018/917, Reg. (EU) 2019/707, Reg. (EU) 2020/869, Reg. (EU) 2021/843, Reg. (EU) No 540/2011, Reg. (EU) No 823/2012
Gefahrenübersicht	A skin irritant and weak sensitizerMinimal to moderate acute toxicityNot likely to be carcinogenic to humans[Reference #1] A skin sensitizer[PubChem] In high-dose animal studies, causes kidney damage[RTECS] May cause irritation[MSDSonline]
Special Reports	USEPA Office of Prevention, Pesticides and Toxic Substances, Pesticide Fact Sheet for Cyazofamid, Reason for Issuance: New Chemical (September 2004)[Available from, as of October 11, 2012: http://iaspub.epa.gov/apex/pesticides/f?p=CHEMICALSEARCH:1]
FIFRA-Anforderungen	Tolerances are established for residues of the fungicide cyazofamid, including its metabolites and degradates, in or on the commodities in the following table. Compliance with the tolerance levels specified in the following table is to be determined by measuring only the sum of 4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide and its metabolite, 4-chloro-5-(4-methylphenyl)-1H-imidazole-2-carbonitrile, calculated as the stoichiometric equivalent of cyazofamid, in or on the following commodities:[Table#7176]Time-limited tolerances are established for residues of the fungicide cyazofamid, including its metabolites and degradates, in or on the commodities in the following table. Compliance with the tolerance levels specified in the following table is to be determined by measuring only the sum of cyazofamid, 4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide and its metabolite CCIM, 4-chloro-5-(4-methylphenyl)-1H-imidazole-2-carbonitrile, calculated as the stoichiometric equivalent of cyazofamid, resulting from use of the pesticide under FIFRA section 18 emergency exemptions. The tolerances expire and are revoked on the date specified in the table.[Table#7177]

Anwendungen & Verwendung

Verwenden

Cyazofamid is a imidazole fungicide for use on food crops.