AM-694
Grundinformationen
- CAS
335161-03-0- Standard-SMILES
O=C(c1ccccc1I)c1cn(CCCCCF)c2ccccc12- InChIKey
LFFIIZFINPPEMC-UHFFFAOYSA-N- Summenformel
- C20H19FINO
- Durchschnittliche Molmasse
- 435,3 g/mol
- Monoisotopische Masse
- 435,04954
Überblick
1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole is a member of the class of indoles that is 1H-indole which is substituted at position 1 by a 5-fluoropentyl group and a position 3 by an o-fluorobenzoyl group. It is a selective agonist for the CB1 cannabinoid receptor; Ki values for the CB1 and CB2 receptors are 0.08 and 1.44 nM, respectively. It has a role as a cannabinoid receptor agonist. It is a member of indoles, an organoiodine compound, an organofluorine compound, a synthetic cannabinoid and an aromatic ketone.
Namen und Bezeichner
- Bevorzugter Name
- AM-694
- IUPAC
- [1-(5-fluoropentyl)indol-3-yl]-(2-iodophenyl)methanone
- Englischer Name
- AM-694
- Summenformel
- C20H19FINO
- Molmasse
- 435.27
Namen und Synonyme
AM-6941-(5-fluoropentyl)-3-(2-iodobenzoyl)indoleAM694AM 6946RK7KN7L1ODEA No. 7694J2.929.919FCHEBI:1380171-[(5-Fluoropentyl)-1H-indol-3-yl]-(2-iodophenyl)methanone1-((5-FLUOROPENTYL)-1H-INDOL-3-YL)-(2-IODOPHENYL)METHANONEMETHANONE, (1-(5-FLUOROPENTYL)-1H-INDOL-3-YL)(2-IODOPHENYL)-AM694 cpd
Weitere Namen anzeigen
AM694 (exempt preparation)AM-694 (1-(5-Fluoropentyl)-3-(2-iodobenzoyl)-indole)1-(5-fluoropentyl)-3-[(2-iodophenyl)carbonyl]-1H-indoleMethanone, [1-(5-fluoropentyl)-1H-indol-3-yl](2-iodophenyl)-AM-694 (1-(5-Fluoropentyl)-3-(2-iodobenzoyl)indole) 1.0 mg/ml in AcetonitrileAM-694 (1-(5-Fluoropentyl)-3-(2-iodobenzoyl)indole) 0.1 mg/ml in Acetonitrile
RefChem:556857335161-03-0UNII-6RK7KN7L1O[1-(5-Fluoropentyl)-1H-indol-3-yl](2-iodophenyl)methanone[1-(5-fluoropentyl)indol-3-yl]-(2-iodophenyl)methanoneSCHEMBL16755254SCHEMBL29385295SCHEMBL29567887
Datenbank-Bezeichner
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 5,3
- Polarare Oberfläche (TPSA)
- 22 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 2
- Frei drehbare Bindungen
- 7
- Schwere Atome
- 24
- Formalladung
- 0
- Komplexität
- 418
Experimentelle und physikochemische Eigenschaften
Drugs
DEA NFLIS-Drug Category -> Synthetic Cannabinoids
DEA Schedule I Controlled Substance -> Cannabimimetic agents
Synthetic Cannabinoids
Pharmaceuticals -> Synthetic Cannabinoids or Psychoactive Compounds
Collision Cross Section181.96 Ų [M+H]+
Physikochemische Eigenschaften
- Siedepunkt
- 546.7 · 546.7±40.0 °C(Predicted)
- Dichte
- 1.46 · 1.46
- Löslichkeit
- 10 mg/ml; · DMF: 10 mg/ml; DMSO: 14 mg/ml; Ethanol: 10 mg/ml
- Aggregatzustand
- A crystalline solid
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Danger
H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Gefahrenhinweise
Regulatory InformationDEA schedule I controlled substance
Sicherheitsdaten
- DEA Controlled Substances
- CSCN: 7694CSA SCH: Schedule INARC: No
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological ClassificationCompounds that interact with and stimulate the activity of CANNABINOID RECEPTORS.
Anwendungen
BeschreibungAM694 is a potent synthetic cannabinoid (CB) with Ki values of 0.08 and 1.44 nM for the CB1 and CB2 receptors, respectively. The physiological actions and metabolism of AM694 have not been characterized.
VerwendenA synthetic cannabimimetic indole derivative which acts as a potent and selective agonist for the cannabinoid receptor CB1.
Zugehörige Reaktionen
0
Keine Reaktionsaufzeichnungen unter den aktuellen Filterkriterien.
Notizen zur Verbindung
Wird geladen…