HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Naringin dihydrochalcone
Naringin DC · Naringine DC · Senior saccharin · Naringin dihydrochal · NARINGINDIHYDROHALCONE · NAGINGINDIHYDROCHALCONE · NARINGIN DIHYDROCHALCONE · NARINGIN DIHYDOROCHALCONE
Identifikatoren & physikalische Daten
| CAS No. | 18916-17-1 |
|---|---|
| Summenformel | C27H34O14 |
| Durchschnittliche Molmasse | 582,5 g/mol |
| Monoisotopische Masse | 582,19485575 g/mol |
| SMILES | C[C@@H]1O[C@@H](O[C@H]2[C@H](Oc3cc(O)c(C(=O)CCc4ccc(O)cc4)c(O)c3)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O |
| InChIKey | CWBZAESOUBENAP-QVNVHUMTSA-N |
| PubChem CID | 9894584 |
| ChEMBL | CHEMBL5308388 |
| ChEBI | CHEBI:184078 |
| EC No. | 700-320-7 |
| DTXSID | DTXSID10940428 |
Chemische & physikalische Eigenschaften
| XLogP | -0,3 |
|---|---|
| Polarare Oberfläche (TPSA) | 236 |
| H-Brücken-Donoren | 9 |
| H-Brücken-Akzeptoren | 14 |
| Frei drehbare Bindungen | 9 |
| Schwere Atome | 41 |
| Formalladung | 0 |
| Komplexität | 827 |
| Löslichkeit | SolubleSoluble (in ethanol)Soluble in DMSO |
| Physical Description | White solid, Bland aroma |
| Schmelzpunkt | 131-132°C |
| Siedepunkt | 916.8±65.0 °C(Predicted) |
| Dichte | 1.63±0.1 g/cm3(Predicted) |
| Dampfdruck | 0Pa at 20-50℃ |
| FEMA | 4495 | NARINGIN DIHYDROCHALCONE |
| Lagerbedingungen | under inert gas (nitrogen or Argon) at 2-8°C |
| Aggregatzustand | Powder |
| pKa (Säurekonstante) | 6.85±0.40(Predicted) |
| Farbe | White to Off-white |
| JECFA Number | 2208 |
| Hauptanwendungen | food and beverages |
| InChIKey | CWBZAESOUBENAP-CUDWAMJSNA-N |
| SMILES | O1[C@H]([C@@H]([C@@H]([C@H]([C@@H]1C)O)O)O)O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O)CO)Oc3cc(c(c(c3)O)C(=O)CCc4ccc(cc4)O)O |
| LogP (Verteilungskoeffizient) | -0.703-1.01 at 22.6℃ and pH5-9 |
| CAS Datenbank | 18916-17-1(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | Not ClassifiedReported as not meeting GHS hazard criteria by 100 of 112 companiesAggregated GHS information provided per 112 reports by companies from 3 notifications to the ECHA C&L Inventory.Reported as not meeting GHS hazard criteria per 100 of 112 reports by companies.There are 2 notifications provided by 12 of 112 reports by companies with hazard statement code(s).Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Regulatorische Informationen | Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)Status: Active Update: 24-10-2014 https://echa.europa.eu/registration-dossier/-/registered-dossier/11444 |
| Hazard Classes and Categories | Not Classified |
| Wassergefährdungsklasse (WGK) | WGK 1 |
| Zollcode | 29329990 |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrenklasse | Acute Tox. 4 Oral |
Anwendungen & Verwendung
Beschreibung
Naringin dihydrochalcone is an artificial sweetener and flavonoid that has been isolated from various plants and has antioxidant activity. It scavenges ABTS (Item No. 27317), oxygen, and 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in cell free assays (IC50s = 24, 322.8, and 318.9 μM, respectively).
Verwenden
Naringin Dihydrochalcone is an intense sweetener and strong antioxidant compound which displays anti-allegeric activity.