Romurtide
Grundinformationen
- CAS
78113-36-7- Standard-SMILES
CCCCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)CC[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](C)O[C@@H]([C@H](O)[C@H](O)CO)[C@H](C=O)NC(C)=O)C(N)=O)C(=O)O- InChIKey
IKSJCVFYCIKDTB-GZZWOGMVSA-N- Summenformel
- C43H78N6O13
- Durchschnittliche Molmasse
- 887,1 g/mol
- Monoisotopische Masse
- 886,56268656
Überblick
Romurtide is a small molecule drug. Romurtide has a monoisotopic molecular weight of 886.56 Da.
Namen und Bezeichner
- Bevorzugter Name
- Romurtide
- IUPAC
- (2S)-2-[[(4R)-4-[[(2S)-2-[[(2R)-2-[(2R,3R,4R,5R)-2-acetamido-4,5,6-trihydroxy-1-oxohexan-3-yl]oxypropanoyl]amino]propanoyl]amino]-5-amino-5-oxopentanoyl]amino]-6-(octadecanoylamino)hexanoic acid
- Englischer Name
- Romurtide
- Summenformel
- C43H78N6O13
- Molmasse
- 887.11
Namen und Synonyme
SUP956TPT6DTXSID401318575romurutideRefChem:930877DTXCID901748381N(alpha)-(N-acetylmuramyl-alanyl-isoglutaminyl)-N(epsilon)stearoyllysine78113-36-7L-Lysine, N2-(N2-(N-(N-acetylmuramoyl)-L-alanyl)-D-alpha-glutaminyl)-N6-(1-oxooctadecyl)-MDP-Lys(L18)MuroctasinNopiaRomurtida
Weitere Namen anzeigen
C13187dj-7041MuroetasinMuroctasineAc-muramyl-AMDP-LYS(L 18)Romurtide USP/EP/BP
RomurtideRomurtidumROMURTIDE [INN]ROMURTIDE [JAN]ROMURTIDE [MI]ROMURTIDE [WHO-DD]orb1983691TP2405
Datenbank-Bezeichner
- CAS
78113-36-7- PubChem CID
- 9940969
- DTXSID
DTXSID401318575- ChEMBL
CHEMBL1908331- UNII
- SUP956TPT6
- EC Number
- 636-074-1
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 3,6
- Polarare Oberfläche (TPSA)
- 313 Ų
- H-Brücken-Donoren
- 10
- H-Brücken-Akzeptoren
- 13
- Frei drehbare Bindungen
- 39
- Schwere Atome
- 62
- Formalladung
- 0
- Komplexität
- 1.340
Physikochemische Eigenschaften
- Schmelzpunkt
- 176 · 176-178°
- Siedepunkt
- 1220.7 · 1220.7±65.0 °C(Predicted)
- Dichte
- 1.163 · 1.163±0.06 g/cm3(Predicted)
- storage temp.
- 20 °C · −20°C
- pka
- 5.7 · 5.70(at 25℃)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 40 reports by companies from 2 notifications to the ECHA C&L Inventory.
Gefahrenhinweise
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Sicherheitsdaten
- wgk
- 3
- RTECS-Nr.
- OL5545000
- Toxizität
- LD50 in male, female mice, male, female rats, dogs (mg/kg): 436, 625, 761, 801, >200 s.c. (Ono)
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.
Anwendungen
BeschreibungRomurtide is a muramyl dipeptide which augments the production of G-CSF. The compound is indicated as an immunomodulator for the treatment of leukopenia caused by anticancer chemotherapy/radiotherapy and also thrombopenia.
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
Anbieter19 Anbieter
LGM Pharma1-(800)-881-8210 · [email protected]
上海鸿肽生物科技有限公司15318089928 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
Creative Peptides[email protected]
太原百利恒康生物技术有限公司19135651983 · [email protected]
Wuhan NCE Biomedical Co.,Ltd.4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
广州爱纯医药科技有限公司020-39119399 18927568969 · [email protected]
杭州专肽生物技术有限公司17342063383 · [email protected]
杭州固拓生物科技有限公司0571-88211921 17357109671 · [email protected]
南京肽谷生物科技有限公司18115476705 · [email protected]
浙江杰坤生物科技有限公司15397062932 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 18917919676 · [email protected]
ANHUI BYERSEN BIOTECH CO. LTD+8617355064950 · [email protected]
南京肽研生物科技有限公司19961912513 19941518170 · [email protected]
Nanjing TGpeptide+86-13347807150 · [email protected]
绍兴市均宇生物科技有限公司0571-0571-88211921 19105816207 · [email protected]
Dideu Industries Group Limited+86-29-81148696 +86-15129568250 · [email protected]
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