Ubiquinol
Grundinformationen
- CAS
5677-55-4- Standard-SMILES
COc1c(O)c(C)c(C/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CCC=C(C)C)c(O)c1OC- InChIKey
QNTNKSLOFHEFPK-UPTCCGCDSA-N- Summenformel
- C59H92O4
- Durchschnittliche Molmasse
- 865,4 g/mol
- Monoisotopische Masse
- 864,69956141
Überblick
Ubiquinol-10 is a ubiquinol in which the polyprenyl substituent is decaprenyl. It has a role as a metabolite and a biomarker. It is an ubiquinol and a polyprenylhydroquinone.
Namen und Bezeichner
- Bevorzugter Name
- Ubiquinol
- IUPAC
- 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methylbenzene-1,4-diol
- Englischer Name
- Reduced Coenzyme Q10
- Summenformel
- C59H92O4
- Molmasse
- 865.36
Namen und Synonyme
ubiquinolreduced coenzyme Q10Ubiquinone hydroquinoneM9NL0C577Y1,4-Benzenediol, 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl-2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methylbenzene-1,4-diol1,4-Benzenediol, 2-((2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl)-5,6-dimethoxy-3-methyl-CHEBI:17976CoQH2reduced ubiquinoneRefChem:192853Ubiquinols
Weitere Namen anzeigen
Reduced Ubiquinone Q10CoQH2-10Ubiquinol 50Liposomal QHQ10UbiquinolWater Soluble Q10Ubiquinol solutionUbiquinol (1705334)
992-78-9Dihydrocoenzyme Q10ubiquinol-10Ubiquinol [WHO-DD]CoQ10H22-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaen-1-yl]-5,6-dimethoxy-3-methylbenzene-1,4-diolMFCD119738162-((2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaen-1-yl)-5,6-dimethoxy-3-methylbenzene-1,4-diol
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 20,2
- Polarare Oberfläche (TPSA)
- 58,9 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 4
- Frei drehbare Bindungen
- 31
- Schwere Atome
- 63
- Formalladung
- 0
- Komplexität
- 1.600
Experimentelle und physikochemische Eigenschaften
DrugsPharmaceuticals -> Listed in ZINC15
CosmeticsCosmetic ingredients (Ubiquinol) -> CIR (Cosmetic Ingredient Review)
Physical DescriptionSolid
Physikochemische Eigenschaften
- Schmelzpunkt
- 48 · 48-49°C
- Siedepunkt
- 866.9 · 866.9±65.0 °C(Predicted)
- Dichte
- 0.951 · 0.951±0.06 g/cm3(Predicted)
- storage temp.
- -20 °C · Amber Vial, -20°C Freezer, Under Inert Atmosphere
- Löslichkeit
- Chloroform: soluble
- Aggregatzustand
- A crystalline solid
- pka
- 10.53 · 10.53±0.50(Predicted)
- Major Application
- pharmaceutical (small molecule)
- InChIKey
- QNTNKSLOFHEFPK-UPTCCGCDSA-N
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
Toxikologische Informationen
Toxicity SummarySafe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org
Sicherheitsdaten
- wgk
- WGK 3
- hs_code
- 2909500000
- Speicherklasse
- 11 - Combustible Solids
Chemie und Industrie
Pharmakologische Informationen
Cellular LocationsExtracellular
Verwendung und Herstellung
UsesCIR ingredient: Ubiquinol
Anwendungen
BeschreibungUbiquinol is a reduced form of coenzyme Q10 (CoQ10; ), which exists in three redox states: fully oxidized (CoQ10/ubiquinone), partially reduced (semiquinone/ubisemiquinone), and fully reduced (ubiquinol). CoQ10 acts as an electron shuttle in the electron transport chain via its reduction to ubiquinol between mitochondrial complexes I and II, also known as NADH dehydrogenase and succinate dehydrogenase, respectively, and mitochondrial complex III, also known as cytochrome bc1 complex. CoQ10 is also reduced to ubiquinol by ferroptosis suppressor protein 1 (FSP1) with NADPH as a cofactor, and ubiquinol traps lipid peroxyl radicals and inhibits lipid peroxidation helping to prevent ferroptosis.
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郑州阿尔法化工有限公司+86-18530059196 · [email protected]
南京凯美西化工有限公司02558748998 18951874644 · [email protected]
LIDE PHARMACEUTICALS LIMITED+852-55945652 · [email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
Shenzhen Varror Biotech Co., Ltd+undefined+86-15817492830 · [email protected]
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