Ethyl 4-(2-Aminopyrid-3-yloxy)butyrate → Ethyl 4-(2-(11-Carbomethoxyundecanoylamino)pyrid-3-yloxy)butyrate
Reaktionsgleichung
[NH2:1][C:2]1[C:7]([O:8][CH2:9][CH2:10][CH2:11][C:12]([O:14][CH2:15][CH3:16])=[O:13])=[CH:6][CH:5]=[CH:4][N:3]=1.[C:17]([O:32][CH3:33])(=[O:31])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][C:28]([O-])=[O:29]>>[C:17]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][C:28]([NH:1][C:2]1[C:7]([O:8][CH2:9][CH2:10][CH2:11][C:12]([O:14][CH2:15][CH3:16])=[O:13])=[CH:6][CH:5]=[CH:4][N:3]=1)=[O:29])([O:32][CH3:33])=[O:31]Komponenten
3
Versuchsvorschrift
When (41) and (7) are reacted as per the procedure of step (E), above, the title compound (42) is obtained. Hydrolysis will yield the corresponding di-acid (4-(2-(11- Carboxyundecanoylamino)pyrid-3-yloxy)butyric acid (43).
Quellen und Nachweise
- ORD-Eintrag
- ord-9935e6e5f83a44eb83fd04849ae79657
- Quelldatensatz
- uspto-grants-2000_04