4-Bromobenzohydrazide → 2-(4-Bromophenyl)-5-methyl-1,3,4-oxadiazole

Beteiligte Stoffe

Reaktionsschritte

A stirred suspension of 4-bromobenzoic hydrazide (4.0 g, 18.6 mmol) in triethyl orthoacetate (15 ml) was heated under reflux for 24 h. The reaction mixture was cooled and the precipitate filtered, washed with 60-80° C. petroleum ether (20 ml) and dried to give the title compound as a yellow solid (3.86 g, 87%).

Herkunft & Nachweise