Bromocyclopentane → 2-Cyclopentyloxy-3,4-dimethoxybenzonitrile
Reaktionsgleichung
[OH:1][C:2]1[C:9]([O:10][CH3:11])=[C:8]([O:12][CH3:13])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[CH:14]1(Br)[CH2:18][CH2:17][CH2:16][CH2:15]1>>[CH:14]1([O:1][C:2]2[C:9]([O:10][CH3:11])=[C:8]([O:12][CH3:13])[CH:7]=[CH:6][C:3]=2[C:4]#[N:5])[CH2:18][CH2:17][CH2:16][CH2:15]1Komponenten
3
Versuchsvorschrift
The subtitle compound was prepared from 2-hydroxy-3,4-dimethoxybenzonitrile and freshly distilled cyclopentyl bromide following the procedure described in Example 10(d). The crude product was purified on silica gel eluting with dichloromethane to give the subtitle compound as a colourless oil (95%). Rf 0.50 (dichloromethane). MS m/z 265 MNH4)+.
Aufarbeitung
- customThe crude product was purified on silica gel eluting with dichloromethane