HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Carbamate → [5-(3,5-dichlorophenyl)sulfanyl-4-isopropyl-1-(4-pyridylmethyl)imidazol-2-yl]methyl N-octanoylcarbamate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Carbamate | HCID 276 | — |
| Edukt | {5-[(3,5-Dichlorophenyl)sulfanyl]-4-isopropyl-1-((pyridin-4-YL)methyl)imidazol-2-YL}methanol | HCID 9844329 | — |
| Edukt | Octanoyl isocyanate | HCID 18791988 | — |
| Produkt | [5-(3,5-dichlorophenyl)sulfanyl-4-isopropyl-1-(4-pyridylmethyl)imidazol-2-yl]methyl N-octanoylcarbamate | HCID 478193 | 56% |
Reaktionsschritte
The compound 89 (101-1048 (816 mg, 2.00 mmol) was converted to the carbamate with octanoyl isocyanate (5 eq.) in the same manner as the example 66 to give the compound 91 (650 mg, 56%) as crystals. Mp. 139-141° C. Rf 0.34 (EtOAc).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06054591 |
| Quelldatensatz | uspto-grants-2000_04 |
| ORD ID | ord-e73b23b2ac694e30b105f27a1b58e5b1 |
| Quellennotiz | uspto-grants-2000_04 |