HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Carbamate → [5-(3,5-dichlorophenyl)sulfanyl-4-isopropyl-1-(4-pyridylmethyl)imidazol-2-yl]methyl N-decanoylcarbamate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Carbamate | HCID 276 | — |
| Edukt | {5-[(3,5-Dichlorophenyl)sulfanyl]-4-isopropyl-1-((pyridin-4-YL)methyl)imidazol-2-YL}methanol | HCID 9844329 | — |
| Edukt | Decanoyl isocyanate | HCID 15011855 | — |
| Produkt | [5-(3,5-dichlorophenyl)sulfanyl-4-isopropyl-1-(4-pyridylmethyl)imidazol-2-yl]methyl N-decanoylcarbamate | HCID 478194 | 42% |
Reaktionsschritte
The compound 89 (245 mg, 0.6 mmol) was converted to the carbamate with decanoyl isocyanate (5 eq.) in the same manner as the example 66 to give the compound 92 (152 mg, 42%) as crystals. Mp. 84-86° C. Rf 0.37 (EtOAc).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06054591 |
| Quelldatensatz | uspto-grants-2000_04 |
| ORD ID | ord-6e2163ec579545659117e6fe89acb1f5 |
| Quellennotiz | uspto-grants-2000_04 |