Methylamine → N,2-Dimethyl-3-pyridinecarboxamide
Reaktionsgleichung
[CH3:1][C:2]1[N:12]=[CH:11][CH:10]=[CH:9][C:3]=1[C:4](OCC)=[O:5].[CH3:13][NH2:14]>CO>[CH3:1][C:2]1[N:12]=[CH:11][CH:10]=[CH:9][C:3]=1[C:4]([NH:14][CH3:13])=[O:5]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Reaktionsbedingungen
- Temperatur
- 50 °C
Versuchsvorschrift
To ethyl 2-methylnicotinate (24.2 g) was added a solution of 40% methylamine in methanol (150 ml), which was then heated in a sealed tube at 50° C. overnight. The reaction mixture was evaporated, to give the title compound as a pale yellow solid (20.781 g, yield; 95%).
Aufarbeitung
- customThe reaction mixture was evaporated
Quellen und Nachweise
- ORD-Eintrag
- ord-5185a0c1e0ae4625a178ecb3812d55ed
- Quelldatensatz
- uspto-grants-2004_09
- Patentnummer
- US06790844B2
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