[NH2:1][CH2:2][CH2:3][NH:4][CH2:5][CH2:6][NH:7][C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9].CS[C:17](SC)=[CH:18][N+:19]([O-:21])=[O:20].C(N(CC)CC)C>C(#N)C>[C:11]([O:10][C:8]([NH:7][CH2:6][CH2:5][N:4]1[CH2:3][CH2:2][NH:1][C:17]1=[CH:18][N+:19]([O-:21])=[O:20])=[O:9])([CH3:14])([CH3:13])[CH3:12]A stirred mixture of 2.03 gram (0.010 mole) of N-{2-[(2-aminoethyl)amino]ethyl}(tert-butoxy)carboxamide (commercially available), 1.18 gram (0.010 mole) of 1,1-di(methylthio)-2-nitroethene and 2 mL (excess) of triethylamine in 40 mL of acetonitrile was warmed to reflux where it was maintained for four hours. After this time the reaction mixture was concentrated under reduced pressure to a solid residue. The residue was washed with diethyl ether and dried, yielding 1.76 grams of the subject compound. The NMR spectrum was consistent with the proposed structure.
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