Hexane → HCID 178516446, Verbindung

HRID 1013706Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1013706
CC1(C)O[C:6](=[O:8])[C:5](=[CH:9][NH:10][C:11]2[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=2)C(=O)O1.CCCCCC>C1(OC2C=CC=CC=2)C=CC=CC=1>[N:10]1[C:11]2[C:12](=[CH:13][N:14]=[CH:15][CH:16]=2)[C:6]([OH:8])=[CH:5][CH:9]=1

Komponenten

4

Edukt 2

HCID 8058HexaneHCID 59427333HCID 59427333, Verbindung

Produkt 1

HCID 178516446HCID 178516446, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7583Diphenyl EtherLösungsmittel

Versuchsvorschrift

A solution of 2,2-dimethyl-5-((pyridin-4-ylamino)methylene)-1,3-dioxane-4,6-dione (1.149 g, 4.63 mmol) in diphenyl ether was heated at 200° C. for 20 min, then cooled to RT. Hexane was added and the mixture was stirred at RT for 30 mins. The solid was filtered off and washed with hexane to furnish 1,6-naphthyridin-4-ol as an off-brown solid.

Aufarbeitung

  1. filtrationThe solid was filtered off
  2. washwashed with hexane

Quellen und Nachweise

ORD-Eintrag
ord-267ed64a8b2f41e38cae9e1febb81757
Quelldatensatz
uspto-grants-2011_07
Patentnummer
US07981891B2

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