Phosphorus oxide (P4O10) → 1-Methyl-5,6-dimethoxy-3,4-dihydro-isoquinoline

HRID 1015042Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1015042
[CH3:1][O:2][C:3]1[C:8]([O:9][CH3:10])=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:11][CH2:12][NH:13][C:14](=O)[CH3:15].O=P12OP3(OP(OP(O3)(O1)=O)(=O)O2)=O>>[CH3:1][O:2][C:3]1[C:8]([O:9][CH3:10])=[CH:7][CH:6]=[C:5]2[C:4]=1[CH2:11][CH2:12][N:13]=[C:14]2[CH3:15]

Komponenten

3

Edukt 2

HCID 14812Phosphorus oxide (P4O10)HCID 47308767N-[2-(2,3-Dimethoxy-phenyl)-ethyl]-acetamide

Produkt 1

HCID 138591851-Methyl-5,6-dimethoxy-3,4-dihydro-isoquinoline

Versuchsvorschrift

In close analogy to the procedure described above, N-[2-(2,3-dimethoxy-phenyl)-ethyl]-acetamide is reacted with phosphorus pentoxide to provide the title compound.

Quellen und Nachweise

ORD-Eintrag
ord-cc04a783188940a299525ce224b3a216
Quelldatensatz
uspto-grants-2011_07
Patentnummer
US07985753B2

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