5-Nitro-1,2,3,4-tetrahydroisoquinoline → HCID 24810788, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[CH:3]=[N:4][C:5]2[N:6]([N:8]=[C:9]([C:11]([OH:13])=O)[CH:10]=2)[CH:7]=1.[N+:14]([C:17]1[CH:26]=[CH:25][CH:24]=[C:23]2[C:18]=1[CH2:19][CH2:20][NH:21][CH2:22]2)([O-:16])=[O:15]>>[Cl:1][C:2]1[CH:3]=[N:4][C:5]2[N:6]([N:8]=[C:9]([C:11]([N:21]3[CH2:20][CH2:19][C:18]4[C:23](=[CH:24][CH:25]=[CH:26][C:17]=4[N+:14]([O-:16])=[O:15])[CH2:22]3)=[O:13])[CH:10]=2)[CH:7]=1Komponenten
3
Versuchsvorschrift
In close analogy to the procedure described in Example 1, 6-chloro-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is reacted with 5-Nitro-1,2,3,4-tetrahydro-isoquinoline to provide the title compound in moderate yield.
Quellen und Nachweise
- ORD-Eintrag
- ord-84f2cc6e4abe45b79b6f9828b5976587
- Quelldatensatz
- uspto-grants-2011_07
- Patentnummer