4-(1-Hydroxy-4-oxocyclohexyl)benzonitrile → 6-(1-Hydroxy-4-oxocyclohexyl)nicotinonitrile

HRID 1016001Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1016001
[OH:1][C:2]1([C:12]2[CH:19]=[CH:18][C:15]([C:16]#[N:17])=[CH:14][N:13]=2)[CH2:11][CH2:10][C:5]2(OCC[O:6]2)[CH2:4][CH2:3]1.OC1(C2C=CC(C#N)=CC=2)CCC(=O)CC1>>[OH:1][C:2]1([C:12]2[CH:19]=[CH:18][C:15]([C:16]#[N:17])=[CH:14][N:13]=2)[CH2:11][CH2:10][C:5](=[O:6])[CH2:4][CH2:3]1

Komponenten

3

Edukt 2

HCID 667872294-(1-Hydroxy-4-oxocyclohexyl)benzonitrileHCID 667877276-(8-Hydroxy-1,4-dioxaspiro[4.5]dec-8-yl)nicotinonitrile

Produkt 1

HCID 667880036-(1-Hydroxy-4-oxocyclohexyl)nicotinonitrile

Versuchsvorschrift

The title compound was synthesized from 6-(8-hydroxy-1,4-dioxaspiro[4.5]dec-8-yl)nicotinonitrile using the sane typical deprotection procedure as for 4-(1-hydroxy-4-oxocyclohexyl)benzonitrile.

Quellen und Nachweise

ORD-Eintrag
ord-a2ee24e6ebe249b6ae7c324569defbfe
Quelldatensatz
uspto-grants-2011_07
Patentnummer
US07985730B2

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