HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Methoxy-5-nitro-2-(pyrrolidin-1-yl)pyridine → 4-Methoxy-2-(pyrrolidin-1-yl)-5-aminopyridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Methoxy-5-nitro-2-(pyrrolidin-1-yl)pyridine | HCID 57431518 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Produkt | 4-Methoxy-2-(pyrrolidin-1-yl)-5-aminopyridine | HCID 57431519 | 96,3% |
Reaktionsschritte
The method described in Stage 12.2 is followed, starting from 1.5 g (6.72 mmol) of 4-methoxy-5-nitro-2-(pyrrolidin-1-yl)-pyridine, obtained in Stage 6.1, and 0.15 g of palladium on charcoal at 10%. We thus obtain 1.25 g of the expected product.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08716272B2 |
| Quelldatensatz | uspto-grants-2014_05 |
| ORD ID | ord-d364502db64e4717960a377a22893ca1 |
| Quellennotiz | uspto-grants-2014_05 |