HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-Thiophen-2-yl-isoxazole-3-carbaldehyde → {1-[2-(7-Methoxy-quinoxalin-2-ylsulfanyl)-ethyl]-piperidin-4-yl}-(5-thiophen-2-yl-isoxazol-3-ylmethyl)-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-Thiophen-2-yl-isoxazole-3-carbaldehyde | HCID 2776546 | — |
| Edukt | 1-[2-(7-Methoxy-quinoxalin-2-ylsulfanyl)-ethyl]-piperidin-4-ylamine | HCID 66746530 | — |
| Produkt | {1-[2-(7-Methoxy-quinoxalin-2-ylsulfanyl)-ethyl]-piperidin-4-yl}-(5-thiophen-2-yl-isoxazol-3-ylmethyl)-amine | HCID 46852846 | — |
Reaktionsschritte
The title compound is prepared as a yellow oil (57 mg, 52% yield) following Scheme 3 and in analogy to Example 40 using 5-thiophen-2-yl-isoxazole-3-carbaldehyde (43 mg, 0.22 mmol 1.0 eq) and 1-[2-(7-methoxy-quinoxalin-2-ylsulfanyl)-ethyl]-piperidin-4-ylamine (70 mg, 0.22 mmol, 1.0 eq) as starting materials.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08716280B2 |
| Quelldatensatz | uspto-grants-2014_05 |
| ORD ID | ord-2013ed992e934cfa88f8ac9ab912beeb |
| Quellennotiz | uspto-grants-2014_05 |