HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → 2-(2-Pyridyloxy)acetic acid hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | Tert-butyl(pyridin-2-yloxy)acetate | HCID 46168743 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 2-(2-Pyridyloxy)acetic acid hydrochloride | HCID 66975989 | — |
Reaktionsschritte
To a solution of tert-butyl(pyridin-2-yloxy)acetate (0.18 g) in THF (1.5 mL) was added 6 mol/L hydrochloric acid (1.5 mL) at 0° C., and the mixture was warmed to room temperature, and stirred for 2 hr. The solvent was evaporated under reduced pressure, and the resultant solid was recrystallized from ethyl acetate and diisopropyl ether to give the title compound (0.11 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08722662B2 |
| Quelldatensatz | uspto-grants-2014_05 |
| ORD ID | ord-f42aa198ffd049f88bb95d785cff233c |
| Quellennotiz | uspto-grants-2014_05 |